Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

H Luo, CT Vong, H Chen, Y Gao, P Lyu, L Qiu, M Zhao… - Chinese medicine, 2019 - Springer
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis

C Liu, M Rokavec, Z Huang, H Hermeking - Cell Death & Differentiation, 2023 - nature.com
Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for
prevention and therapy of colorectal cancer/CRC. However, the exact mechanism of action …

Curcumin as an alternative epigenetic modulator: mechanism of action and potential effects

F Hassan, MS Rehman, MS Khan, MA Ali… - Frontiers in …, 2019 - frontiersin.org
Curcumin (a polyphenolic compound in turmeric) is famous for its potent anti-inflammatory,
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …

Curcumin and colorectal cancer: An update and current perspective on this natural medicine

W Weng, A Goel - Seminars in cancer biology, 2022 - Elsevier
Colorectal cancer (CRC) is one of most common malignancies worldwide and its incidence
is still growing. In spite of recent advances in targeted therapies, their clinical efficacy has …

Dietary compounds as epigenetic modulating agents in cancer

Á Carlos-Reyes, JS López-González… - Frontiers in …, 2019 - frontiersin.org
Epigenetic mechanisms control gene expression during normal development and their
aberrant regulation may lead to human diseases including cancer. Natural phytochemicals …

Strawberry and human health: Effects beyond antioxidant activity

F Giampieri, JM Alvarez-Suarez… - Journal of agricultural …, 2014 - ACS Publications
The usefulness of a diet rich in vegetables and fruits on human health has been widely
recognized: a high intake of antioxidant and bioactive compounds may in fact play a crucial …

Combinatorial epigenetics impact of polyphenols and phytochemicals in cancer prevention and therapy

I Arora, M Sharma, TO Tollefsbol - International journal of molecular …, 2019 - mdpi.com
Polyphenols are potent micronutrients that can be found in large quantities in various food
sources and spices. These compounds, also known as phenolics due to their phenolic …

[HTML][HTML] Role of short chain fatty acid receptors in intestinal physiology and pathophysiology

M Priyadarshini, KU Kotlo, PK Dudeja… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
Nutrient sensing is a mechanism for organisms to sense their environment. In larger
animals, including humans, the intestinal tract is a major site of nutrient sensing for the body …

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …