Toxoplasmosis: Current and emerging parasite druggable targets

RE Hajj, L Tawk, S Itani, M Hamie, J Ezzeddine… - Microorganisms, 2021 - mdpi.com
Toxoplasmosis is a prevalent disease affecting a wide range of hosts including
approximately one-third of the human population. It is caused by the sporozoan parasite …

Thiazolidin-4-one-based derivatives–Efficient tools for designing antiprotozoal agents. A review of the last decade

H Tuszewska, J Szczepański, S Mandziuk… - Bioorganic Chemistry, 2023 - Elsevier
Thiazolidin-4-one derivatives have a wide range of therapeutic implementations and clinical
significance for medicinal chemistry. This heterocyclic ring has been reported to possess a …

[HTML][HTML] In vitro evaluation of new 4-thiazolidinones on invasion and growth of Toxoplasma gondii

DA Molina, GA Ramos, A Zamora-Vélez… - International Journal for …, 2021 - Elsevier
Treatments for toxoplasmosis such as pyrimethamine have shown numerous side effects. It
has been reported that the likelihood of relapse associated with pyrimethamine-based …

Discovery of potent anti-toxoplasmosis drugs from secondary metabolites in Citrus limon (lemon) leaves, supported in-silico study

MMD Mohammed, HS Mohammed, SAA El Wafa… - Scientific Reports, 2025 - nature.com
Toxoplasmosis induced by Toxoplasma gondii is a well-known health threat, that prompts
fatal encephalitis increased with immunocompromised patients, in addition, it can cause …

Synthesis, Spectroscopic Characterization, and Biological Evaluation of Thiazolidin-4-one Derivatives of Sulfamethoxazole: Insights into ADMET Properties and …

IAA Hamdan, AH Matloob, EA Gatea… - Russian Journal of …, 2023 - Springer
Antibiotic resistance has emerged as a formidable public health challenge, being
recognized as a paramount priority demanding urgent resolution. Consequently, to augment …

In Silico Approaches for Prioritizing Drug Targets in Pathogens

M Santana, SF de Oliveira Tosta, AK Jaiswal… - … Agriculture Reviews 46 …, 2020 - Springer
Antimicrobial resistance is a natural evolutionary process in response to antimicrobial
exposure; however, the indiscriminate use of antimicrobials is accelerating this progression …

Evaluación in vitro del efecto de nuevas Tiazolidinonas sobre la invasión y crecimiento del parásito Toxoplasma gondii

DA Molina Lara - 2020 - bdigital.uniquindio.edu.co
El tratamiento convencional para la toxoplasmosis es una mezcla entre pirimetamina y
sulfadiazina, pero esta quimioterapia presenta efectos secundarios severos. Algunos …

[PDF][PDF] Evaluación in vitro del efecto de nuevas Tiazolidinonas sobre la invasión y crecimiento del parásito Toxoplasma gondii

DAM Lara - 2020 - bdigital.uniquindio.edu.co
Evaluación in vitro del efecto de nuevas Tiazolidinonas sobre la invasión y crecimiento del
parásito Toxoplasma gondii Diego Page 1 i Evaluación in vitro del efecto de nuevas …

[引用][C] Preliminary Green route Synthesis of Substituted Hydrazono Thiazolidin-4-Ones

AP Kaur, N Sharma