The secretion of biotechnologically or pharmaceutically relevant recombinant proteins into
the culture supernatant of a bacterial expression host greatly facilitates their downstream …

Lactic acid bacteria (LAB) are promising vectors of choice to deliver active molecules to
mucosal tissues. They are recognized as safe by the World Health Organization and some …

Engineered living materials (ELMs) are a new class of materials in which living organism
incorporated into diffusive matrices uptake a fundamental role in material's composition and …

Bacillus subtilis and Bacillus licheniformis are widely used for the large-scale industrial
production of proteins. These strains can efficiently secrete proteins into the culture medium …

Nephrolithiasis ranks third among urological diseases in terms of prevalence, making up
about 15% of cases. The continued increase in the incidence of nephrolithiasis is most …

The passage of proteins across biological membranes via the general secretory (Sec)
pathway is a universally conserved process with critical functions in cell physiology and …

Escherichia coli—the powerhouse for recombinant protein production—is rapidly gaining
status as a reliable and efficient host for secretory expression. An improved understanding of …

Bacillus subtilis is widely used for large-scale industrial production of heterologous proteins.
Because of its high intrinsic secretory capacity, it can efficiently secrete proteins into the …

Signal peptides are short peptides directing newly synthesized proteins toward the secretory
pathway. These N-terminal signal sequences are ubiquitous to all prokaryotes and …

The safety status of lactic acid bacteria (LAB) and their capacity to survive the passage
through the gastrointestinal tract (GI tract) have rendered them excellent candidates for the …