Decoding chemical information from vibrational spectroscopy data: Local vibrational mode theory

E Kraka, W Zou, Y Tao - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Modern vibrational spectroscopy is more than just an analytical tool. Information about the
electronic structure of a molecule, the strength of its bonds, and its conformational flexibility …

Two-dimensional correlation spectroscopy (2D-COS) for analysis of spatially resolved vibrational spectra

P Lasch, I Noda - Applied Spectroscopy, 2019 - journals.sagepub.com
The last two decades have seen tremendous progress in the application of two-dimensional
correlation spectroscopy (2D-COS) as a versatile analysis method for data series obtained …

Early-stage lung cancer diagnosis by deep learning-based spectroscopic analysis of circulating exosomes

H Shin, S Oh, S Hong, M Kang, D Kang, Y Ji, BH Choi… - ACS …, 2020 - ACS Publications
Lung cancer has a high mortality rate, but an early diagnosis can contribute to a favorable
prognosis. A liquid biopsy that captures and detects tumor-related biomarkers in body fluids …

Comparative Analysis of Machine Learning Algorithms on Surface Enhanced Raman Spectra of Clinical Staphylococcus Species

JW Tang, QH Liu, XC Yin, YC Pan, PB Wen… - Frontiers in …, 2021 - frontiersin.org
Raman spectroscopy (RS) is a widely used analytical technique based on the detection of
molecular vibrations in a defined system, which generates Raman spectra that contain …

Infrared spectroscopic imaging advances as an analytical technology for biomedical sciences

TP Wrobel, R Bhargava - Analytical chemistry, 2018 - ACS Publications
Optical chemical imaging seeks to nondestructively acquire spatially resolved chemical
information without the use of labels or probes. The combination of vibrational mid-infrared …

Application of vibrational spectroscopy and imaging to point-of-care medicine: a review

S Pahlow, K Weber, J Popp, BR Wood… - Applied …, 2018 - journals.sagepub.com
Vibrational spectroscopy and imaging promise molecular information that can be rapidly
acquired without the need for specialized stains or dyes, thereby potentially simplifying and …

Synchrotron macro ATR-FTIR microspectroscopy for high-resolution chemical mapping of single cells

J Vongsvivut, D Pérez-Guaita, BR Wood, P Heraud… - Analyst, 2019 - pubs.rsc.org
Attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy has been
used widely for probing the molecular properties of materials. Coupling a synchrotron …

Emerging developments in two-dimensional correlation spectroscopy (2D-COS)

Y Park, S Jin, I Noda, YM Jung - Journal of Molecular Structure, 2020 - Elsevier
Noteworthy new progress in 2D correlation spectroscopy (2D-COS) and its versatile
applications for the last two years are compiled in this comprehensive survey review. We …

Fingerprinting a living cell by Raman integrated mid-infrared photothermal microscopy

X Li, D Zhang, Y Bai, W Wang, J Liang… - Analytical …, 2019 - ACS Publications
Vibrational spectroscopic imaging techniques, based on infrared absorption or Raman
scattering, allow for noninvasive chemically specific visualization of biological systems. The …

Multispectral atomic force microscopy-infrared nano-imaging of malaria infected red blood cells

D Perez-Guaita, K Kochan, M Batty, C Doerig… - Analytical …, 2018 - ACS Publications
Atomic force microscopy-infrared (AFM-IR) spectroscopy is a powerful new technique that
can be applied to study molecular composition of cells and tissues at the nanoscale. AFM-IR …