Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models

P Jain, H Kathuria, N Dubey - Biomaterials, 2022 - Elsevier
Tissue/organ shortage is a major medical challenge due to donor scarcity and patient
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …

Natural hydrogel-based bio-inks for 3D bioprinting in tissue engineering: a review

A Fatimi, OV Okoro, D Podstawczyk, J Siminska-Stanny… - Gels, 2022 - mdpi.com
Three-dimensional (3D) printing is well acknowledged to constitute an important technology
in tissue engineering, largely due to the increasing global demand for organ replacement …

Strategies for 3D bioprinting of spheroids: A comprehensive review

D Banerjee, YP Singh, P Datta, V Ozbolat, A O'Donnell… - Biomaterials, 2022 - Elsevier
Biofabricated tissues have found numerous applications in tissue engineering and
regenerative medicine in addition to the promotion of disease modeling and drug …

Multi-lineage human iPSC-derived platforms for disease modeling and drug discovery

A Sharma, S Sances, MJ Workman, CN Svendsen - Cell stem cell, 2020 - cell.com
Human induced pluripotent stem cells (hiPSCs) provide a powerful platform for disease
modeling and have unlocked new possibilities for understanding the mechanisms governing …

[HTML][HTML] 3D bioprinting in cardiac tissue engineering

Z Wang, L Wang, T Li, S Liu, B Guo, W Huang, Y Wu - Theranostics, 2021 - ncbi.nlm.nih.gov
Heart disease is the main cause of death worldwide. Because death of the myocardium is
irreversible, it remains a significant clinical challenge to rescue myocardial deficiency …

[HTML][HTML] The cell in the ink: Improving biofabrication by printing stem cells for skeletal regenerative medicine

G Cidonio, M Glinka, JI Dawson, ROC Oreffo - Biomaterials, 2019 - Elsevier
Recent advances in regenerative medicine have confirmed the potential to manufacture
viable and effective tissue engineering 3D constructs comprising living cells for tissue repair …

Engineering vascularized organoid-on-a-chip models

VS Shirure, CCW Hughes… - Annual Review of …, 2021 - annualreviews.org
Recreating human organ–level function in vitro is a rapidly evolving field that integrates
tissue engineering, stem cell biology, and microfluidic technology to produce 3D organoids …

Bioengineered human blood vessels

LE Niklason, JH Lawson - Science, 2020 - science.org
BACKGROUND Vascular replacement and repair for the treatment of atherosclerotic
disease, infection, and traumatic injury are some of the most commonly performed surgical …

3D Bioprinting of Vascularized Tissues for in vitro and in vivo Applications

EP Chen, Z Toksoy, BA Davis… - Frontiers in Bioengineering …, 2021 - frontiersin.org
With a limited supply of organ donors and available organs for transplantation, the aim of
tissue engineering with three-dimensional (3D) bioprinting technology is to construct fully …

Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances

RZ Zhuang, R Lock, B Liu… - Nature Biomedical …, 2022 - nature.com
Engineered human cardiac tissues facilitate progress in regenerative medicine, disease
modelling and drug development. In this Perspective, we reflect on the most notable …