The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

J. Clin. Invest. 109: 699–705 (2002). DOI: 10.1172/JCI200215277. and acquired immune
responses are coordinated, with innate immunity representing the initial and instructive …

Cystic fibrosis is characterized by an early and sustained influx of inflammatory cells into the
airways and by release of proteases. Resolution of inflammation is normally associated with …

The Pulmonary Immune Effects of Mechanical Ventilation in Pa... : Anesthesia & Analgesia
The Pulmonary Immune Effects of Mechanical Ventilation in Patients Undergoing Thoracic …

Background. Respiratory syncytial virus (RSV) is the most common cause of lower
respiratory tract disease in infants. The role of inflammatory mediators in the pathogenesis of …

Objectives: To review the involvement of coagulation and fibrinolysis in the pathogenesis of
acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), pulmonary infection, and …

Introduction The benefit of corticosteroids as adjunctive treatment in patients with severe
community-acquired pneumonia (CAP) requiring hospital admission remains unclear. This …

Objective To assess the predictive capacity for the diagnosis of ventilator-associated
pneumonia (VAP) of serum procalcitonin levels before and on the day it is suspected …

Objective: To assess the cytokine expression (tumor necrosis factor-α [TNF-α], interleukin [IL]-
1β, and IL-6) in severe pneumonia, both locally (in the lungs) and systemically (in blood) …

BACKGROUND Inflammatory cytokine concentrations correlate with severity of sepsis. We
hypothesised that patients with community acquired pneumonia (CAP) associated with …