The adventitia, the outer layer of the blood vessel wall, may be the most complex layer of the
wall and may be the master regulator of wall physiology and pathobiology. This review …

Bone's remarkable mechanical properties are a result of its hierarchical structure. The
mineralized collagen fibrils, made up of collagen fibrils and crystal platelets, are bone's …

The complex network structure of elastin and collagen extracellular matrix (ECM) forms the
primary load bearing components in the arterial wall. The structural and mechanobiological …

Abstract Design strategies for small diameter vascular grafts are converging toward native-
inspired tissue engineered grafts. A new automated technology is presented that combines …

Two-photon microscopy (TPM) is an attractive biomedical imaging method due to its large
penetration depth and optical sectioning capability. In particular, label-free autofluorescence …

Among the three layers of the aortic wall, the media is primarily responsible for its
mechanical properties, but the adventitia prevents the aorta from overstretching and …

Coronary atherosclerosis is the major cause of mortality and disability in developed nations.
A deeper understanding of mechanical properties of coronary arteries and hence their …

The load bearing properties of large blood vessels are principally conferred by collagen and
elastin networks and their microstructural organization plays an important role in the …

Producing thinner polymer membranes has been a research hotspot to satisfy the increasing
demand from diverse application scenarios in the industry. This work used biaxially …

Collagen plays a key role in the strength of aortic walls, so studying micro-structural changes
during disease development is critical to better understand collagen reorganization. Second …