The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

More than one year since its emergence, corona virus disease 2019 (COVID-19) is still
looming large with a paucity of treatment options. To add to this burden, a sizeable subset of …

In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

In humans, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is highly
infective, often causes severe acute and/or long-term illness, and elicits a high rate of …

The vulnerability of humankind to SARS-CoV-2 in the absence of a pre-existing immunity,
the unpredictability of the infection outcome, and the high transmissibility, broad tissue …

The innate immune system protects the host from external pathogens and internal damage
in various ways. The cGAS-STING signaling pathway, comprised of cyclic GMP-AMP …

Hyperinflammation characterized by elevated proinflammatory cytokines known as 'cytokine
storms' is the major cause of high severity and mortality seen in COVID‐19 patients. The …

Dysregulated inflammatory responses are often correlated with disease severity during viral
infections. Annexin A1 (AnxA1) is an endogenous pro-resolving protein that timely regulates …

Coronavirus disease 2019 (COVID-19) is an epidemic respiratory disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that can cause infections in …

Abstract Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Emerging evidence indicates that …