Proline and its derivatives as organocatalysts for multi‐component reactions in aqueous media: synergic pathways to the green synthesis of heterocycles

BS Vachan, M Karuppasamy, P Vinoth… - Advanced Synthesis …, 2020 - Wiley Online Library
Proline is a non‐toxic and inexpensive natural amino acid that is readily available in both
enantiomeric forms and was one of the very first compounds to be studied as an …

L-Proline: A versatile organo-catalyst in organic chemistry

BR Thorat, SN Mali, SS Wavhal… - … Chemistry & High …, 2023 - ingentaconnect.com
Background: L-proline is a natural amino acid having secondary amine functionality and
acts as a bifunctional catalyst (organo-catalyst). The amino-functional group acts as Lewis …

Iridium supported on porous polypyridine-oxadiazole as high-activity and recyclable catalyst for the borrowing hydrogen reaction

J Li, A Mao, W Yao, H Zhu, D Wang - Green Chemistry, 2022 - pubs.rsc.org
Homogenization of heterogeneous catalysts is a valuable and interesting research topic.
Porous polypyridine-oxadiazole (PPO), as not only a carrier but also a ligand, was designed …

Diels–Alder cycloaddition reactions in sustainable media

MIL Soares, AL Cardoso, TMVD Pinho e Melo - Molecules, 2022 - mdpi.com
Diels–Alder cycloaddition reaction is one of the most powerful strategies for the construction
of six-membered carbocyclic and heterocyclic systems, in most cases with high regio-and …

Greener synthesis of nitrogen-containing heterocycles in water, PEG, and bio-based solvents

JF Campos, S Berteina-Raboin - Catalysts, 2020 - mdpi.com
The solvents used in chemistry are a fundamental element of the environmental
performance of processes in corporate and academic laboratories. Their influence on costs …

An MEDT study of the mechanism and selectivities of the [3+ 2] cycloaddition reaction of tomentosin with benzonitrile oxide

A Zeroual, M Ríos‐Gutiérrez, M El Idrissi… - … Journal of Quantum …, 2019 - Wiley Online Library
Abstract The [3+ 2] cycloaddition (32CA) reaction of tomentosin with benzonitrile oxide
yielding a spiro‐isoxazoline has been studied within the Molecular Electron Density Theory …

L-Proline: Unraveling its Reactivity and Mechanistic Insights as an Organocatalyst in Multi-Component Synthesis: A Comprehensive Review

BS Saikia, I Rahman, P Nath, A Boruah, ML Deb… - Catalysis …, 2024 - Taylor & Francis
ABSTRACT L-Proline has emerged as a cornerstone in organocatalysis, celebrated for its
versatility and efficiency in promoting a wide range of chemical transformations. This review …

Recent developments in the synthesis of five-and six-membered N-heterocycles from dicarbonyl compounds

N Kaur, P Bhardwaj, M Gupta - Current Organic Chemistry, 2021 - ingentaconnect.com
Various diketones such as 1, 2-diketones, 1, 3-diketones, 1, 4-diketones, β-diketones and
dicarbonyl compounds are used in the synthesis of core heterocyclic compounds such as …

[HTML][HTML] l-Proline catalyzed synthesis of biologically promising heterocycles under sustainable conditions

R Karmakar, C Mukhopadhyay - Tetrahedron Chem, 2024 - Elsevier
Catalysis field wherein a tiny organic molecule like l-proline is an efficient and selectively
catalyzed organic reaction. Catalyst-supported organic synthesis is confirmed to be involved …

Synthesis of isoxazolo[5,4-b]pyridine derivatives (microreview)

LV Dyadyuchenko, VV Dotsenko - Chemistry of Heterocyclic Compounds, 2021 - Springer
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