Lifetime-engineered NIR-II nanoparticles unlock multiplexed in vivo imaging
Deep tissue imaging in the second near-infrared (NIR-II) window holds great promise for
physiological studies and biomedical applications,,,,–. However, inhomogeneous signal …
physiological studies and biomedical applications,,,,–. However, inhomogeneous signal …
Mesoscopic fluorescence lifetime imaging: Fundamental principles, clinical applications and future directions
Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …
Real-time molecular imaging of near-surface tissue using Raman spectroscopy
The steady progress in medical diagnosis and treatment of diseases largely hinges on the
steady development and improvement of modern imaging modalities. Raman spectroscopy …
steady development and improvement of modern imaging modalities. Raman spectroscopy …
Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment
The biannual International Conference on Biophotonics was recently held on April 30 to May
1, 2017, in Fremantle, Western Australia. This continuing conference series brought together …
1, 2017, in Fremantle, Western Australia. This continuing conference series brought together …
Intraoperative margin assessment in oral and oropharyngeal cancer using label-free fluorescence lifetime imaging and machine learning
Objective: To demonstrate the diagnostic ability of label-free, point-scanning, fiber-based
Fluorescence Lifetime Imaging (FLIm) as a means of intraoperative guidance during oral …
Fluorescence Lifetime Imaging (FLIm) as a means of intraoperative guidance during oral …
Autofluorescence lifetime augmented reality as a means for real-time robotic surgery guidance in human patients
Due to loss of tactile feedback the assessment of tumor margins during robotic surgery is
based only on visual inspection, which is neither significantly sensitive nor specific. Here we …
based only on visual inspection, which is neither significantly sensitive nor specific. Here we …
Real-time diagnosis and visualization of tumor margins in excised breast specimens using fluorescence lifetime imaging and machine learning
Tumor-free surgical margins are critical in breast-conserving surgery. In up to 38% of the
cases, however, patients undergo a second surgery since malignant cells are found at the …
cases, however, patients undergo a second surgery since malignant cells are found at the …
Real‐time augmented reality for delineation of surgical margins during neurosurgery using autofluorescence lifetime contrast
A Alfonso‐Garcia, J Bec… - Journal of …, 2020 - Wiley Online Library
Current clinical brain imaging techniques used for surgical planning of tumor resection lack
intraoperative and real‐time feedback; hence surgeons ultimately rely on subjective …
intraoperative and real‐time feedback; hence surgeons ultimately rely on subjective …
Real-time multispectral fluorescence lifetime imaging using single photon avalanche diode arrays
Autofluorescence spectroscopy has emerged in recent years as a powerful tool to report
label-free contrast between normal and diseased tissues, both in vivo and ex vivo. We report …
label-free contrast between normal and diseased tissues, both in vivo and ex vivo. We report …
Dual excitation spectral autofluorescence lifetime and reflectance imaging for fast macroscopic characterization of tissues
AI Herrando, M Castillo-Martin, A Galzerano… - Biomedical Optics …, 2024 - opg.optica.org
Advancements in optical imaging techniques have revolutionized the field of biomedical
research, allowing for the comprehensive characterization of tissues and their underlying …
research, allowing for the comprehensive characterization of tissues and their underlying …