The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

Background Impairments in affective cognition are part of the neurocognitive profile and
possible treatment targets in bipolar disorder (BD), but the findings are heterogeneous. The …

Objective Cognitive dysfunction is common in both schizophrenia and bipolar disorder. This
is a meta-analysis of studies that compared cognitive dysfunction between schizophrenia …

Many studies have reported that heavy substance use is associated with impaired response
inhibition. Studies typically focused on associations with a single substance, while …

Introduction Decreased sociability is a symptom of psychiatric conditions including autism-
spectrum disorder and schizophrenia. Both of these conditions are associated with …

Background Cognitive impairments are prominent in schizophrenia (SZ). Imaging studies
have demonstrated that functional changes of several areas of the brain exist in SZ patients …

Anhedonia is a hallmark feature of depression and is highly prevalent among individuals
with mood disorders. The history and neurobiology of anhedonia has been most extensively …

Effortful motivation and reward valuation learning deficits are associated with negative
symptoms and impaired cognition in schizophrenia (SZ) patients. Whereas clinical …

Repeated exposure to stress during childhood is associated with increased risk for
neuropsychiatric illness, substance use disorders and other behavioral problems in …

Bipolar spectrum disorders (BSDs) and substance use disorders (SUDs) are associated with
neural reward dysfunction. However, it is unclear what pattern of neural reward function …