Identifying cancer prognosis genes through causal learning

S Wu, C Yin, Y Wang, H Sun - Briefings in Bioinformatics, 2025 - academic.oup.com
Accurate identification of causal genes for cancer prognosis is critical for estimating disease
progression and guiding treatment interventions. In this study, we propose CPCG (Cancer …

ALLSTAR: inference of reliAble causaL ruLes between Somatic muTAtions and canceR phenotypes

D Simionato, A Collesei, F Miglietta, F Vandin - Bioinformatics, 2024 - academic.oup.com
Motivation Recent advances in DNA sequencing technologies have allowed the detailed
characterization of genomes in large cohorts of tumors, highlighting their extreme …

[HTML][HTML] Functional Assessments of Gynecologic Cancer Models Highlight Differences Between Single-Node Inhibitors of the PI3K/AKT/mTOR Pathway and a Pan …

A Broege, S Rossetti, A Sen, AS Menon, I MacNeil… - Cancers, 2024 - mdpi.com
Abstract Background/Objectives: The PI3K/AKT/mTOR (PAM) pathway is frequently activated
in gynecological cancers. Many PAM inhibitors selectively target single PAM pathway …

Identifying cooperative genes causing cancer progression with dynamic causal inference

AM Cifuentes-Bernal, L Liu, J Li, TD Le - bioRxiv, 2023 - biorxiv.org
Cancer progression is driven by complex gene interactions, which are not fully understood
due to the dynamic and multifaceted nature of the disease. Traditional methods for …

Statistical Learning Techniques for Causal Structure Discovery and Effect Estimation

D Simionato - 2024 - research.unipd.it
The increasing availability of data and the decreasing computational power cost sparked the
data-revolution that we are in nowadays, with machine learning and artificial intelligence …

ALLSTAR: un nuovo algoritmo bioinformatico per inferire regole causali tra mutazioni somatiche e fenotipi tumorali

A Collesei - 2024 - research.unipd.it
Motivation: Recent advances in DNA sequencing technologies have allowed the detailed
characterization of genomes in large cohorts of tumors, highlighting their extreme …