The role of dietary fatty acids in the pathology of metabolic syndrome
AM Lottenberg, M da Silva Afonso… - The Journal of nutritional …, 2012 - Elsevier
Dysfunctional lipid metabolism is a key component in the development of metabolic
syndrome, a very frequent condition characterized by dyslipidemia, insulin resistance …
syndrome, a very frequent condition characterized by dyslipidemia, insulin resistance …
11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects
Abstract 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) interconverts the inactive
glucocorticoid cortisone and its active form cortisol. It is widely expressed and, although …
glucocorticoid cortisone and its active form cortisol. It is widely expressed and, although …
11beta-Hydroxysteroid dehydrogenase type 1 inhibitors: novel agents for the treatment of metabolic syndrome and obesity-related disorders?
OBJECTIVE: Metabolic syndrome (MetS) and Cushing's syndrome share common features.
It has been proposed that increased glucocorticoid activity at peripheral tissues may play a …
It has been proposed that increased glucocorticoid activity at peripheral tissues may play a …
Kefir reduces insulin resistance and inflammatory cytokine expression in an animal model of metabolic syndrome
DD Rosa, ŁM Grześkowiak, CLLF Ferreira… - Food & function, 2016 - pubs.rsc.org
There is growing evidence that kefir can be a promising tool in decreasing the risk of many
diseases, including metabolic syndrome (MetS). The aim of the present study was to …
diseases, including metabolic syndrome (MetS). The aim of the present study was to …
Naringin reverses hepatocyte apoptosis and oxidative stress associated with HIV-1 nucleotide reverse transcriptase inhibitors-induced metabolic complications
OO Adebiyi, OA Adebiyi, PMO Owira - Nutrients, 2015 - mdpi.com
Nucleoside Reverse Transcriptase Inhibitors (NRTIs) have not only improved therapeutic
outcomes in the treatment of HIV infection but have also led to an increase in associated …
outcomes in the treatment of HIV infection but have also led to an increase in associated …
Investigation of brain-derived neurotrophic factor (BDNF) gene expression in hypothalamus of obese rats: Modulation by omega-3 fatty acids
SM Abdel-Maksoud, SI Hassanein… - Nutritional …, 2017 - Taylor & Francis
Purpose: The aim of this study was investigating the effect of omega-3 fatty acids (ω-3 FAs)
on brain-derived neurotrophic factor (BDNF) gene expression, using in vivo and in vitro …
on brain-derived neurotrophic factor (BDNF) gene expression, using in vivo and in vitro …
Novel 2-(Adamantan-1-ylamino)Thiazol-4(5H)-One Derivatives and Their Inhibitory Activity towards 11β-HSD1—Synthesis, Molecular Docking and In Vitro Studies
R Studzińska, D Kupczyk, W Płaziński… - International Journal of …, 2021 - mdpi.com
A common mechanism in which glucocorticoids participate is suggested in the pathogenesis
of such metabolic diseases as obesity, metabolic syndrome, or Cushing's syndrome. The …
of such metabolic diseases as obesity, metabolic syndrome, or Cushing's syndrome. The …
Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue
C Veyrat-Durebex, N Deblon, A Caillon, R Andrew… - PLoS …, 2012 - journals.plos.org
Glucocorticoids (GCs) are involved in multiple metabolic processes, including the regulation
of insulin sensitivity and adipogenesis. Their action partly depends on their intracellular …
of insulin sensitivity and adipogenesis. Their action partly depends on their intracellular …
Carbenoxolone treatment ameliorated metabolic syndrome in WNIN/Ob obese rats, but induced severe fat loss and glucose intolerance in lean rats
SSV Prasad Sakamuri, M Sukapaka, VK Prathipati… - PLoS …, 2012 - journals.plos.org
Background 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) regulates local
glucocorticoid action in tissues by catalysing conversion of inactive glucocorticoids to active …
glucocorticoid action in tissues by catalysing conversion of inactive glucocorticoids to active …
Altered or impaired immune response upon vaccination in WNIN/Ob rats
P Bandaru, H Rajkumar, G Nappanveettil - Vaccine, 2011 - Elsevier
The present study was aimed to study the immune response in three months old male and
female naïve obese animals and upon hepatitis B vaccination in three months old female …
female naïve obese animals and upon hepatitis B vaccination in three months old female …