[HTML][HTML] Vaccine adjuvants: mechanisms and platforms

T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

Manganese‐based tumor immunotherapy

K Zhang, C Qi, K Cai - Advanced Materials, 2023 - Wiley Online Library
As an essential micronutrient, manganese (Mn) participates in various physiological
processes and plays important roles in host immune system, hematopoiesis, endocrine …

[HTML][HTML] SARS-CoV-2 vaccines based on the spike glycoprotein and implications of new viral variants

D Martínez-Flores, J Zepeda-Cervantes… - Frontiers in …, 2021 - frontiersin.org
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

[HTML][HTML] Adjuvants for coronavirus vaccines

Z Liang, H Zhu, X Wang, B Jing, Z Li, X Xia… - Frontiers in …, 2020 - frontiersin.org
Vaccine development utilizing various platforms is one of the strategies that has been
proposed to address the coronavirus disease 2019 (COVID-19) pandemic. Adjuvants are …

Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity

S Shi, H Zhu, X Xia, Z Liang, X Ma, B Sun - Vaccine, 2019 - Elsevier
In conjugate, inactivated, recombinant, and toxoid vaccines, adjuvants are extensively and
essentially used for enhanced and long-lasting protective immune responses. Depending …

MnOx Nanospikes as Nanoadjuvants and Immunogenic Cell Death Drugs with Enhanced Antitumor Immunity and Antimetastatic Effect

B Ding, P Zheng, F Jiang, Y Zhao… - Angewandte Chemie …, 2020 - Wiley Online Library
Despite the widespread applications of manganese oxide nanomaterials (MONs) in
biomedicine, the intrinsic immunogenicity of MONs is still unclear. MnOx nanospikes (NSs) …

[HTML][HTML] Inorganic nanosheets facilitate humoral immunity against medical implant infections by modulating immune co-stimulatory pathways

C Yang, Y Luo, H Shen, M Ge, J Tang, Q Wang… - Nature …, 2022 - nature.com
Strategies to manipulate immune cell co-inhibitory or co-activating signals have
revolutionized immunotherapy. However, certain immunologically cold diseases, such as …

Recent development of pH‐responsive theranostic nanoplatforms for magnetic resonance imaging‐guided cancer therapy

X Li, R Yue, G Guan, C Zhang, Y Zhou, G Song - Exploration, 2023 - Wiley Online Library
The acidic characteristic of the tumor site is one of the most well‐known features and
provides a series of opportunities for cancer‐specific theranostic strategies. In this regard …

Chemical strategies to boost cancer vaccines

WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …