[HTML][HTML] The progression of geographic atrophy secondary to age-related macular degeneration

M Fleckenstein, P Mitchell, KB Freund, SV Sadda… - Ophthalmology, 2018 - Elsevier
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD)
that leads to progressive and irreversible loss of visual function. Geographic atrophy is …

Age-related macular degeneration: a review

M Fleckenstein, S Schmitz-Valckenberg… - JAMA, 2024 - jamanetwork.com
Importance Age-related macular degeneration (AMD) affects approximately 20 million
people in the US and 196 million people worldwide. AMD is a leading cause of severe …

[HTML][HTML] Consensus nomenclature for reporting neovascular age-related macular degeneration data: consensus on neovascular age-related macular degeneration …

RF Spaide, GJ Jaffe, D Sarraf, KB Freund, SR Sadda… - Ophthalmology, 2020 - Elsevier
Purpose To establish a process to evaluate and standardize a state-of-the-art nomenclature
for reporting neovascular age-related macular degeneration (AMD) data. Design Consensus …

Consensus definition for atrophy associated with age-related macular degeneration on OCT: classification of atrophy report 3

SR Sadda, R Guymer, FG Holz, S Schmitz-Valckenberg… - Ophthalmology, 2018 - Elsevier
Purpose To develop consensus terminology and criteria for defining atrophy based on OCT
findings in the setting of age-related macular degeneration (AMD). Design Consensus …

Incomplete retinal pigment epithelial and outer retinal atrophy in age-related macular degeneration: classification of atrophy meeting report 4

RH Guymer, PJ Rosenfeld, CA Curcio, FG Holz… - Ophthalmology, 2020 - Elsevier
Purpose To describe the defining features of incomplete retinal pigment epithelium (RPE)
and outer retinal atrophy (iRORA), a consensus term referring to the OCT-based anatomic …

Age-related macular degeneration

M Fleckenstein, TDL Keenan, RH Guymer… - Nature reviews Disease …, 2021 - nature.com
Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …

Soft drusen in age-related macular degeneration: biology and targeting via the oil spill strategies

CA Curcio - Investigative ophthalmology & visual science, 2018 - iovs.arvojournals.org
AMD is a major cause of legal blindness in older adults approachable through
multidisciplinary research involving human tissues and patients. AMD is a vascular …

Imaging features associated with progression to geographic atrophy in age-related macular degeneration: classification of atrophy meeting report 5

GJ Jaffe, U Chakravarthy, KB Freund, RH Guymer… - Ophthalmology …, 2021 - Elsevier
Purpose To provide an image-based description of retinal features associated with risk for
development of geographic atrophy (GA) in eyes with age-related macular degeneration …

Fundus autofluorescence imaging

S Schmitz-Valckenberg, M Pfau, M Fleckenstein… - Progress in retinal and …, 2021 - Elsevier
Fundus autofluorescence (FAF) imaging is an in vivo imaging method that allows for
topographic mapping of naturally or pathologically occurring intrinsic fluorophores of the …

Activated retinal pigment epithelium, an optical coherence tomography biomarker for progression in age-related macular degeneration

CA Curcio, EC Zanzottera, T Ach… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: To summarize and contextualize recent histology and clinical imaging publications
on retinal pigment epithelium (RPE) fate in advanced age-related macular degeneration …