In vivo rodent erythrocyte micronucleus assay

M Hayashi, RR Tice, JT MacGregor, D Anderson… - … mutagenesis and related …, 1994 - Elsevier
The following summary represents a consensus of the working group except where noted.
The items discussed are listed in the order in which they appear in the OECD guideline …

In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated …

M Hayashi, JT MacGregor… - Environmental and …, 2000 - Wiley Online Library
An expert working group on the in vivo micronucleus assay, formed as part of the
International Workshop on Genotoxicity Test Procedures (IWGTP), discussed protocols for …

Evaluation of the rat micronucleus test with bone marrow and peripheral blood: Summary of the 9th collaborative study by CSGMT/JEMS· MMS

A Wakata, Y Miyamae, S Sato, T Suzuki… - Environmental and …, 1998 - Wiley Online Library
The mouse has traditionally been used for the micronucleus test, with bone marrow the
usual target organ. The aim of the 9th collaborative study by CSGMT was to evaluate the …

Comparison of flow cytometry-and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and …

KL Witt, E Livanos, GE Kissling, DK Torous… - … /Genetic Toxicology and …, 2008 - Elsevier
The development of automated flow cytometric (FCM) methods for evaluating micronucleus
(MN) frequencies in erythrocytes has great potential for improving the sensitivity …

In vivo erythrocyte micronucleus assay: III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion …

M Hayashi, JT MacGregor, DG Gatehouse… - … /Genetic Toxicology and …, 2007 - Elsevier
The in vivo micronucleus assay working group of the International Workshop on Genotoxicity
Testing (IWGT) discussed new aspects in the in vivo micronucleus (MN) test, including the …

Evaluation of the rodent micronucleus assay by a 28‐day treatment protocol: Summary of the 13th Collaborative Study by the Collaborative Study Group for the …

S Hamada, S Sutou, T Morita, A Wakata… - Environmental and …, 2001 - Wiley Online Library
To examine whether micronucleus tests can be incorporated into general toxicology assays,
we performed micronucleus tests applying the treatment protocols typically used in such …

Short-term screening method for the prediction of carcinogenicity of chemical substances: current status and problems of an in vivo rodent micronucleus assay

S Sato, I Tomita - Journal of Health Science, 2001 - jstage.jst.go.jp
Various short-term screening methods have been developed to detect mutagenic/
carcinogenic substances. They have played important roles not only in screening suspected …

Three‐color labeling method for flow cytometric measurement of cytogenetic damage in rodent and human blood

SD Dertinger, K Camphausen… - Environmental and …, 2004 - Wiley Online Library
Experiments described herein were designed to evaluate the performance characteristics of
a flow cytometry-based system that scores the incidence of peripheral blood micronucleated …

RETRACTED: Using structural equation modeling to assess the genotoxic and mutagenic effects of heavy metal contamination in the freshwater ecosystems: A study …

JG da Silva, CA Chagas, TG dos Santos Souza… - 2024 - Elsevier
Post-publication, an investigation conducted on behalf of the journal by Elsevier's Research
Integrity & Publishing Ethics team determined that 1 of the reviews for this manuscript was …

Polyphenolic contents of Teucrium polium L. and Teucrium scordium L. associated with their protective effects against MMC-induced chromosomal damage in cultured …

OM DJORDJEVIC, MR JAKOVLJEVIC… - Turkish Journal of …, 2018 - journals.tubitak.gov.tr
Teucrium species have been used in traditional medicine for treatment of different diseases.
The aim of this study was to investigate polyphenolic contents by high-performance liquid …