Environment-responsive nanophores for therapy and treatment monitoring via molecular MRI quenching

C Kaittanis, TM Shaffer, A Ogirala, S Santra… - Nature …, 2014 - nature.com
The effective delivery of therapeutics to disease sites significantly contributes to drug
efficacy, toxicity and clearance. Here we demonstrate that clinically approved iron oxide …

Performance of optoacoustic and fluorescence imaging in detecting deep-seated fluorescent agents

Z Chen, XL Deán-Ben, S Gottschalk… - Biomedical optics …, 2018 - opg.optica.org
Fluorescent contrast agents are widely employed in biomedical research. While many
studies have reported deep tissue imaging of fluorescent moieties using either fluorescence …

Quantitative tomographic imaging of intermolecular FRET in small animals

V Venugopal, J Chen, M Barroso… - Biomedical optics express, 2012 - opg.optica.org
Forster resonance energy transfer (FRET) is a nonradiative transfer of energy between two
fluorescent molecules (a donor and an acceptor) in nanometer range proximity. FRET …

Förster resonance energy transfer photoacoustic microscopy

Y Wang, LV Wang - Journal of Biomedical Optics, 2012 - spiedigitallibrary.org
Förster, or fluorescence, resonance energy transfer (FRET) provides fluorescence signals
sensitive to intra-and inter-molecular distances in the 1 to 10 nm range. Widely applied in …

Fabrication and application of heterogeneous printed mouse phantoms for whole animal optical imaging

BZ Bentz, AV Chavan, D Lin, EHR Tsai, KJ Webb - Applied optics, 2016 - opg.optica.org
This work demonstrates the usefulness of 3D printing for optical imaging applications.
Progress in developing optical imaging for biomedical applications requires customizable …

In vivo fluorescence lifetime tomography of a FRET probe expressed in mouse

J McGinty, DW Stuckey, VY Soloviev… - Biomedical optics …, 2011 - opg.optica.org
Förster resonance energy transfer (FRET) is a powerful biological tool for reading out cell
signaling processes. In vivo use of FRET is challenging because of the scattering properties …

Theory of speckle intensity correlations over object position in a heavily scattering random medium

KJ Webb, Q Luo - Physical Review A, 2020 - APS
We present a general theory for optical imaging of moving objects obscured by heavily
scattering random media. Measurements involve collecting a series of speckle intensity …

In vivo mouse fluorescence imaging for folate-targeted delivery and release kinetics

EHR Tsai, BZ Bentz, V Chelvam, V Gaind… - Biomedical Optics …, 2014 - opg.optica.org
Many cancer cells over-express folate receptors, and this provides an opportunity for both
folate-targeted fluorescence imaging and the development of targeted anti-cancer drugs. We …

Multiresolution localization with temporal scanning for super-resolution diffuse optical imaging of fluorescence

BZ Bentz, D Lin, JA Patel… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
A super-resolution optical imaging method is presented that relies on the distinct temporal
information associated with each fluorescent optical reporter to determine its spatial position …

Deep-tissue photoacoustic tomography of Förster resonance energy transfer

Y Wang, J Xia, LV Wang - Journal of biomedical optics, 2013 - spiedigitallibrary.org
Förster resonance energy transfer (FRET) is a distance-dependent process that transfers
excited state energy from a donor molecule to an acceptor molecule without the emission of …