A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity
The blood–brain barrier is playing a critical role in controlling the influx and efflux of
biological substances essential for the brain's metabolic activity as well as neuronal function …
biological substances essential for the brain's metabolic activity as well as neuronal function …
Pathophysiology of blood–brain barrier permeability throughout the different stages of ischemic stroke and its implication on hemorrhagic transformation and recovery
The blood–brain barrier (BBB) is a dynamic interface responsible for maintaining the central
nervous system homeostasis. Its unique characteristics allow protecting the brain from …
nervous system homeostasis. Its unique characteristics allow protecting the brain from …
The influence of neuroinflammation in Autism Spectrum Disorder
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised
by deficits in social communication and restricted or repetitive behaviours. The clinical …
by deficits in social communication and restricted or repetitive behaviours. The clinical …
Translational research in traumatic brain injury
D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …
contributing to nearly one-third of all injury related deaths in the United States and exacting …
Central fatigue: the serotonin hypothesis and beyond
The original central fatigue hypothesis suggested that an exercise-induced increase in
extracellular serotonin concentrations in several brain regions contributed to the …
extracellular serotonin concentrations in several brain regions contributed to the …
Biomarkers in traumatic brain injury (TBI): a review
A Dadas, J Washington, R Diaz-Arrastia… - … disease and treatment, 2018 - Taylor & Francis
Biomarkers can be broadly defined as qualitative or quantitative measurements that convey
information on the physiopathological state of a subject at a certain time point or disease …
information on the physiopathological state of a subject at a certain time point or disease …
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight
As spaceflight becomes more common with commercial crews, blood-based measures of
crew health can guide both astronaut biomedicine and countermeasures. By profiling …
crew health can guide both astronaut biomedicine and countermeasures. By profiling …
Seizure‐promoting effect of blood–brain barrier disruption
Purpose: It is generally accepted that blood–brain barrier (BBB) failure occurs as a result of
CNS diseases, including epilepsy. However, evidences also suggest that BBB failure may …
CNS diseases, including epilepsy. However, evidences also suggest that BBB failure may …
Blood-brain barrier protection as a therapeutic strategy for acute ischemic stroke
AE Sifat, B Vaidya, TJ Abbruscato - The AAPS Journal, 2017 - Springer
The blood-brain barrier (BBB) is a vital component of the neurovascular unit (NVU)
containing tight junctional (TJ) proteins and different ion and nutrient transporters which …
containing tight junctional (TJ) proteins and different ion and nutrient transporters which …
Serum S100β: A noninvasive marker of blood‐brain barrier function and brain lesions
BACKGROUND S100β protein is expressed constitutively by brain astrocytes. Elevated
S100β levels in cerebrospinal fluid and serum reported after head trauma, subarachnoid …
S100β levels in cerebrospinal fluid and serum reported after head trauma, subarachnoid …