The neuronal organization of the retina

RH Masland - Neuron, 2012 - cell.com
The mammalian retina consists of neurons of> 60 distinct types, each playing a specific role
in processing visual images. They are arranged in three main stages. The first decomposes …

Retinal bipolar cells: elementary building blocks of vision

T Euler, S Haverkamp, T Schubert… - Nature Reviews …, 2014 - nature.com
Retinal bipolar cells are the first'projection neurons' of the vertebrate visual system—all of
the information needed for vision is relayed by this intraretinal connection. Each of the at …

Congenital stationary night blindness: an analysis and update of genotype–phenotype correlations and pathogenic mechanisms

C Zeitz, AG Robson, I Audo - Progress in retinal and eye research, 2015 - Elsevier
Congenital stationary night blindness (CSNB) refers to a group of genetically and clinically
heterogeneous retinal disorders. Seventeen different genes with more than 360 different …

Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration

D Križaj, S Cordeiro, O Strauß - Progress in Retinal and eye Research, 2023 - Elsevier
Transient receptor potential (TRP) channels are a widely expressed family of 28
evolutionarily conserved cationic ion channels that operate as primary detectors of chemical …

Two-photon imaging of nonlinear glutamate release dynamics at bipolar cell synapses in the mouse retina

BG Borghuis, JS Marvin, LL Looger… - Journal of …, 2013 - Soc Neuroscience
Alpha/Y-type retinal ganglion cells encode visual information with a receptive field
composed of nonlinear subunits. This nonlinear subunit structure enhances sensitivity to …

Divergent outer retinal circuits drive image and non-image visual behaviors

C Beier, U Bocchero, L Levy, Z Zhang, N Jin… - Cell reports, 2022 - cell.com
Image-and non-image-forming vision are essential for animal behavior. Here we use
genetically modified mouse lines to examine retinal circuits driving image-and non-image …

Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer

J Ou, C Vijayasarathy, L Ziccardi… - The Journal of …, 2015 - Am Soc Clin Investig
Strategies aimed at invoking synaptic plasticity have therapeutic potential for several
neurological conditions. The human retinal synaptic disease X-linked retinoschisis (XLRS) is …

The auxiliary calcium channel subunit α2δ4 is required for axonal elaboration, synaptic transmission, and wiring of rod photoreceptors

Y Wang, KE Fehlhaber, I Sarria, Y Cao, NT Ingram… - Neuron, 2017 - cell.com
Neural circuit wiring relies on selective synapse formation whereby a presynaptic release
apparatus is matched with its cognate postsynaptic machinery. At metabotropic synapses …

GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes

C Orlandi, E Posokhova, I Masuho, TA Ray… - Journal of Cell …, 2012 - rupress.org
The extent and temporal characteristics of G protein–coupled receptor (GPCR) signaling are
shaped by the regulator of G protein signaling (RGS) proteins, which promote G protein …

Pregnenolone sulfate: from steroid metabolite to TRP channel ligand

C Harteneck - Molecules, 2013 - mdpi.com
Pregnenolone sulfate is a steroid metabolite with a plethora of actions and functions. As a
neurosteroid, pregnenolone sulfate modulates a variety of ion channels, transporters, and …