Plant‐derived compounds as potential leads for new drug development targeting COVID‐19

L Liu, M Kapralov, M Ashton - Phytotherapy Research, 2024 - Wiley Online Library
COVID‐19, which was first identified in 2019 in Wuhan, China, is a respiratory illness
caused by a virus called severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …

[PDF][PDF] Discovery of potential inhibitors of the receptor-binding domain (RBD) of pandemic disease-causing SARS-CoV-2 Spike Glycoprotein from Triphala through …

SL Khan, FA Siddiqui, MS Shaikh, NV Nema… - Current Chinese …, 2021 - academia.edu
Background: COVID-19 (SARS-CoV-2 infection) has affected almost every region of the
world. Presently, there is no defined line of treatment available for it. Triphala is already …

Design, synthesis, and in silico studies of novel N-(2-aminophenyl)-2, 3-diphenylquinoxaline-6-sulfonamide derivatives targeting receptor-binding domain (RBD) of …

FA Siddiqui, SL Khan, RP Marathe… - Letters in Drug Design …, 2021 - ingentaconnect.com
Background: Pneumonia induced by a novel coronavirus (SARS-CoV-2) was named
coronavirus disease 2019 (COVID-19). The Receptor-binding domain (RBD) of SARS-CoV …

Looking for SARS-coV-2 therapeutics through computational approaches

M Vincenzi, FA Mercurio… - Current Medicinal …, 2023 - ingentaconnect.com
Background: In the last few years, in silico tools, including drug repurposing coupled with
structure-based virtual screening, have been extensively employed to look for anti-COVID …

Computational evaluation of quinones of Nigella sativa L. as potential inhibitor of dengue virus NS5 methyltransferase

M Roney, A Dubey, MH Nasir, AM Huq… - Journal of …, 2023 - Taylor & Francis
Aedes aegypti is the primary vector for the transmission of the dengue virus, which causes
dengue fever, dengue hemorrhagic illness and dengue shock syndrome. There is now no …

Structure-based virtual screening methods for the identification of novel phytochemical inhibitors targeting furin protease for the management of COVID-19

P Kumar Tiwari, M Chouhan, R Mishra… - Frontiers in Cellular …, 2024 - frontiersin.org
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus, is a highly contagious respiratory disease with …

[HTML][HTML] Screening and evaluation of cytotoxicity and antiviral effects of secondary metabolites from water extracts of Bersama abyssinica against SARS-CoV-2 Delta

N Zekeya, B Mamiro, H Ndossi, RC Mallya… - … Medicine and Therapies, 2022 - Springer
Background Bersama abyssinica is a common herb in Africa, with diverse medical uses in
different areas. The plant is well-known in Tanzania for treating respiratory disorders such as …