A bird's eye view of mitochondrial unfolded protein response in cancer: mechanisms, progression and further applications
X Zhang, Y Fan, K Tan - Cell Death & Disease, 2024 - nature.com
Mitochondria are essential organelles that play critical roles in energy metabolism,
apoptosis and various cellular processes. Accumulating evidence suggests that …
apoptosis and various cellular processes. Accumulating evidence suggests that …
[HTML][HTML] ONC206 targeting ClpP induces mitochondrial dysfunction and protective autophagy in hepatocellular carcinoma cells
J Cao, F Cao, C Wang, Z Jiao, Y You, X Wang, W Zhao - Neoplasia, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is the most common form of liver cancer, accounting for
approximately 90% of all cases. ONC201, a member of the imipridone drug family, has …
approximately 90% of all cases. ONC201, a member of the imipridone drug family, has …
Mugen-UMAP: UMAP visualization and clustering of mutated genes in single-cell DNA sequencing data
Abstract Background The application of Uniform Manifold Approximation and Projection
(UMAP) for dimensionality reduction and visualization has revolutionized the analysis of …
(UMAP) for dimensionality reduction and visualization has revolutionized the analysis of …
Deregulated Gene Expression Profiles and Regulatory Networks in Adult and Pediatric RUNX1/RUNX1T1-Positive AML Patients
P Kanellou, I Georgakopoulos-Soares, A Zaravinos - Cancers, 2023 - mdpi.com
Simple Summary AML is a heterogeneous and complex disease. RUNX1/RUNX1T1 is a
fusion oncogene resulting from the chromosomal translocation t (8; 21) and plays a crucial …
fusion oncogene resulting from the chromosomal translocation t (8; 21) and plays a crucial …