S1PR1 modulators in multiple sclerosis: Efficacy, safety, comparison, and chemical structure insights

OJ Kandjani, S Yaqoubi, SS Vahdati… - European Journal of …, 2023 - Elsevier
Multiple sclerosis (MS) is a neurological disease that leads to severe physical and cognitive
disabilities. Drugs used in the treatment of MS vary from small synthetic molecules to large …

Cytokine Secretion Dynamics of Isolated PBMC after Cladribine Exposure in RRMS Patients

R Balasa, S Maier, A Hutanu, S Voidazan… - International Journal of …, 2022 - mdpi.com
Cladribine (CLD) treats multiple sclerosis (MS) by selectively and transiently depleting B and
T cells with a secondary long-term reconstruction of the immune system. This study provides …