Human neuronal maturation comes of age: cellular mechanisms and species differences

JL Wallace, AA Pollen - Nature Reviews Neuroscience, 2024 - nature.com
The delayed and prolonged postmitotic maturation of human neurons, compared with
neurons from other species, may contribute to human-specific cognitive abilities and …

Specialized astrocytes mediate glutamatergic gliotransmission in the CNS

R de Ceglia, A Ledonne, DG Litvin, BL Lind, G Carriero… - Nature, 2023 - nature.com
Multimodal astrocyte–neuron communications govern brain circuitry assembly and function.
For example, through rapid glutamate release, astrocytes can control excitability, plasticity …

Astrocyte heterogeneity and interactions with local neural circuits

MG Holt - Essays in Biochemistry, 2023 - portlandpress.com
Astrocytes are ubiquitous within the central nervous system (CNS). These cells possess
many individual processes which extend out into the neuropil, where they interact with a …

Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses

SM O'Toole, HK Oyibo, GB Keller - Neuron, 2023 - cell.com
Predictive processing postulates the existence of prediction error neurons in cortex. Neurons
with both negative and positive prediction error response properties have been identified in …

Identification of visual cortex cell types and species differences using single-cell RNA sequencing

JR Wei, ZZ Hao, C Xu, M Huang, L Tang, N Xu… - Nature …, 2022 - nature.com
The primate neocortex exerts high cognitive ability and strong information processing
capacity. Here, we establish a single-cell RNA sequencing dataset of 133,454 macaque …

Cell-type-specific inhibitory circuitry from a connectomic census of mouse visual cortex

CM Schneider-Mizell, AL Bodor, D Brittain… - …, 2024 - pmc.ncbi.nlm.nih.gov
Mammalian cortex features a vast diversity of neuronal cell types, each with characteristic
anatomical, molecular and functional properties. Synaptic connectivity powerfully shapes …

Transcriptomic cell-type specificity of local cortical circuits

M Patiño, MA Rossa, WN Lagos, NS Patne… - Neuron, 2024 - cell.com
Complex neocortical functions rely on networks of diverse excitatory and inhibitory neurons.
While local connectivity rules between major neuronal subclasses have been established …

[HTML][HTML] Synaptic gradients transform object location to action

M Dombrovski, MY Peek, JY Park, A Vaccari… - Nature, 2023 - nature.com
To survive, animals must convert sensory information into appropriate behaviours,. Vision is
a common sense for locating ethologically relevant stimuli and guiding motor responses …

Retina-derived signals control pace of neurogenesis in visual brain areas but not circuit assembly

S Sherman, I Arnold-Ammer, MW Schneider… - Nature …, 2023 - nature.com
Brain development is orchestrated by both innate and experience-dependent mechanisms,
but their relative contributions are difficult to disentangle. Here we asked if and how central …

Runx1 controls auditory sensory neuron diversity in mice

BR Shrestha, L Wu, LV Goodrich - Developmental cell, 2023 - cell.com
Sound stimulus is encoded in mice by three molecularly and physiologically diverse
subtypes of sensory neurons, called Ia, Ib, and Ic spiral ganglion neurons (SGNs). Here, we …