Food addiction: a valid concept?

PC Fletcher, PJ Kenny - Neuropsychopharmacology, 2018 - nature.com
Can food be addictive? What does it mean to be a food addict? Do common underlying
neurobiological mechanisms contribute to drug and food addiction? These vexing questions …

Uncontrolled eating: a unifying heritable trait linked with obesity, overeating, personality and the brain

U Vainik, I García‐García… - European Journal of …, 2019 - Wiley Online Library
Many eating‐related psychological constructs have been proposed to explain obesity and
overeating. However, these constructs, including food addiction, disinhibition, hedonic …

Influences of dopaminergic system dysfunction on late-life depression

WD Taylor, DH Zald, JC Felger, S Christman… - Molecular …, 2022 - nature.com
Deficits in cognition, reward processing, and motor function are clinical features relevant to
both aging and depression. Individuals with late-life depression often show impairment …

Alterations in reward network functional connectivity are associated with increased food addiction in obese individuals

S Ravichandran, RR Bhatt, B Pandit, V Osadchiy… - Scientific reports, 2021 - nature.com
Functional neuroimaging studies in obesity have identified alterations in the connectivity
within the reward network leading to decreased homeostatic control of ingestive behavior …

The role of central dopamine and serotonin in human obesity: lessons learned from molecular neuroimaging studies

KA van Galen, KW Ter Horst, J Booij, SE la Fleur… - Metabolism, 2018 - Elsevier
Obesity results from an imbalance between energy intake and expenditure, and many
studies have aimed to determine why obese individuals continue to (over) consume food …

Obesity and dietary fat influence dopamine neurotransmission: Exploring the convergence of metabolic state, physiological stress, and inflammation on dopaminergic …

CW Wallace, SC Fordahl - Nutrition research reviews, 2022 - cambridge.org
The aim of this review is to explore how metabolic changes induced by diets high in
saturated fat (HFD) affect nucleus accumbens (NAc) dopamine neurotransmission and food …

Quantification of the biological age of the brain using neuroimaging

JH Cole, K Franke, N Cherbuin - Biomarkers of human aging, 2019 - Springer
The cosmetic and behavioural aspects of ageing become increasingly apparent with the
passing years. The individual variability in physical ageing can be immediately observed in …

[HTML][HTML] Good practice in food-related neuroimaging

PAM Smeets, A Dagher, TA Hare, S Kullmann… - The American journal of …, 2019 - Elsevier
The use of neuroimaging tools, especially functional magnetic resonance imaging, in
nutritional research has increased substantially over the past 2 decades. Neuroimaging is a …

Striatal dopamine D2-like receptors availability in obesity and its modulation by bariatric surgery: a systematic review and meta-analysis

G Ribeiro, A Maia, G Cotovio, FPM Oliveira… - Scientific Reports, 2023 - nature.com
There is significant evidence linking a 'reward deficiency syndrome'(RDS), comprising
decreased availability of striatal dopamine D2-like receptors (DD2lR) and addiction-like …

Molecular imaging of central dopamine in obesity: A qualitative review across substrates and radiotracers

LK Janssen, A Horstmann - Brain sciences, 2022 - mdpi.com
Dopamine is a neurotransmitter that plays a crucial role in adaptive behavior. A wealth of
studies suggests obesity-related alterations in the central dopamine system. The most direct …