Tailoring nanomaterials for targeting tumor‐associated macrophages
Advances in the field of nanotechnology together with an increase understanding of tumor
immunology have paved the way for the development of more personalized cancer immuno …
immunology have paved the way for the development of more personalized cancer immuno …
Reprogramming tumor-associated macrophages as a unique approach to target tumor immunotherapy
In the last ten years, it has become increasingly clear that tumor-infiltrating myeloid cells
drive not just carcinogenesis via cancer-related inflammatory processes, but also tumor …
drive not just carcinogenesis via cancer-related inflammatory processes, but also tumor …
CSF1/CSF1R signaling inhibitor pexidartinib (PLX3397) reprograms tumor-associated macrophages and stimulates T-cell infiltration in the sarcoma microenvironment
Abstract Colony-stimulating factor 1 (CSF1) is a primary regulator of the survival,
proliferation, and differentiation of monocyte/macrophage that sustains the protumorigenic …
proliferation, and differentiation of monocyte/macrophage that sustains the protumorigenic …
Stimuli-responsive polymer-doxorubicin conjugate: Antitumor mechanism and potential as nano-prodrug
Polymer-drug conjugates has significantly improved the anti-tumor efficacy of
chemotherapeutic drugs and alleviated their side effects. N-(1, 3-dihydroxypropan-2-yl) …
chemotherapeutic drugs and alleviated their side effects. N-(1, 3-dihydroxypropan-2-yl) …
Nanocarriers used in drug delivery to enhance immune system in cancer therapy
Cancer, a group of diseases responsible for the second largest cause of global death, is
considered one of the main public health problems today. Despite the advances, there are …
considered one of the main public health problems today. Despite the advances, there are …
Drug delivery to macrophages: A review of nano-therapeutics targeted approach for inflammatory disorders and cancer
Introduction Macrophages are involved in the normal defense of the body; however, the
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …
Nanomedicine enables spatiotemporally regulating macrophage-based cancer immunotherapy
Cancer immunotherapy, leveraging the host's coordinated immune system to fight against
tumor has been clinically validated. However, the modest response owing to the multiple …
tumor has been clinically validated. However, the modest response owing to the multiple …
[HTML][HTML] Macrophages: Key Players in the Battle against Triple-Negative Breast Cancer
I Padzińska-Pruszyńska, P Kucharzewska… - International Journal of …, 2024 - mdpi.com
Triple-negative breast cancer (TNBC) is a challenging subtype of breast cancer
characterized by the absence of estrogen and progesterone receptors and HER2 …
characterized by the absence of estrogen and progesterone receptors and HER2 …
Emerging nanoparticle strategies for modulating tumor-associated macrophage polarization
L Shi, H Gu - Biomolecules, 2021 - mdpi.com
Immunotherapy has made great progress in recent years, yet the efficacy of solid tumors
remains far less than expected. One of the main hurdles is to overcome the immune …
remains far less than expected. One of the main hurdles is to overcome the immune …
Biorecognition: A key to drug-free macromolecular therapeutics
This review highlights a new paradigm in macromolecular nanomedicine–drug-free
macromolecular therapeutics (DFMT). The effectiveness of the new system is based on …
macromolecular therapeutics (DFMT). The effectiveness of the new system is based on …