Pancreatic cancer and microenvironments: Implications of anesthesia

HC Lai, YW Kuo, YH Huang, SM Chan, KI Cheng… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic cancer is a lethal malignant neoplasm with less than 10% 5-
year relative survival after the initial diagnosis. Several factors may be related to the poor …

[HTML][HTML] The Influence of Regional Anesthesia on the Systemic Stress Response

T Reysner, K Wieczorowska-Tobis, G Kowalski… - Reports, 2024 - mdpi.com
Background: The systemic stress response to surgery is a complex physiological process
characterized by neuroendocrine, sympathetic, and inflammatory activation. While …

Effect of perioperative dexmedetomidine anesthesia on prognosis of elderly patients with gastrointestinal tumor surgery

L Guo, Y Liu, M Wang - Computational and Mathematical …, 2022 - Wiley Online Library
It was to investigate the influence of perioperative dexmedetomidine (DEX) anesthesia on
the prognosis of elderly patients with gastrointestinal tumor (GIT) surgery. 90 patients who …

Neuroprotective effect of HOTAIR silencing on isoflurane-induced cognitive dysfunction via sponging microRNA-129-5p and inhibiting neuroinflammation

Y Wang, S Zhao, G Li, D Wang, Y Jin - Neuroimmunomodulation, 2022 - karger.com
Introduction: This article purposed to detect the function of the HOTAIR and
HOTAIR/microRNA-129-5p (miR-129-5p) axis on the isoflurane (ISO)-injured cells and rat …

[HTML][HTML] OXY-SCORE and Volatile Anesthetics: A New Perspective of Oxidative Stress in EndoVascular Aneurysm Repair—A Randomized Clinical Trial

A Burgos-Santamaría, P Rodríguez-Rodríguez… - International Journal of …, 2024 - mdpi.com
An aortic aneurysm (AA) is a life-threatening condition. Oxidative stress may be a common
pathway linking multiple mechanisms of an AA, including vascular inflammation and …

Protective effects of dexmedetomidine infusion on genotoxic potential of isoflurane in patients undergoing emergency surgery

S Aroosa, A Sattar, A Javeed, M Usman… - … Journal of Clinical …, 2023 - Wiley Online Library
Background. Isoflurane (ISO) has been extensively uses in general anesthesia and reported
to cause deoxyribonucleic acid (DNA) damage in prolonged surgical procedures …

A mini-review of the effects of inhalational and intravenous anesthetics on oxidative stress in dogs

K Tomsič, A Nemec Svete - Frontiers in veterinary science, 2022 - frontiersin.org
General anesthesia increases the production of reactive oxygen species (ROS), which can
exacerbate or increase oxidative stress and thus affect the prognosis of surgical procedures …

Changes in blood oxidative stress biomarker and cholinesterase activity after general vs spinal anesthesia for elective cesarean sections

RS Karam, FK Mohammad - Anaesthesia, Pain & Intensive Care, 2023 - apicareonline.com
Background & Objective: There is an increased ratio of cesarean sections (CS) compared to
normal deliveries the world over. Both general and regional anesthetic techniques are in …

Serum and erythrocyte antioxidant defense in colorectal cancer patients during early postoperative period: potential modifiers and impact on clinical outcomes

M Krzystek-Korpacka, M Mierzchała-Pasierb… - Antioxidants, 2021 - mdpi.com
A better understanding of antioxidant status, its modifiers, and its effect on clinical outcomes
in patients undergoing colorectal cancer surgery is needed for effective antioxidant-based …

Mir-128-3p attenuates the neurotoxicity in rats induced by isoflurane anesthesia

D Qian, S Dai, Y Sun, Y Yuan, L Wang - Neurotoxicity Research, 2022 - Springer
Isoflurane (ISO) has been widely used in clinical anesthesia, and exposure to ISO leads to
cognitive dysfunction. Our paper aimed to investigate the effect of miR-128-3p on cognitive …