Paracoccidioides brasiliensis causes one of the most prevalent systemic mycoses in Latin
America–paracoccidioidomycosis. It is a dimorphic fungus that undergoes a complex …

Pulmonary fibrosis is a form of lung disease that develops due to aberrant wound-healing
following repeated alveoli injury in genetically susceptible individuals, resulting in chronic …

Micose sistêmica endêmica de grande interesse para os países da América Latina, a
paracoccidioidomicose (PCM) é causada pelo fungo termo-dimórfico Paracoccidioides …

Micose sistêmica endêmica de grande interesse para os países da América Latina, a
paracoccidioidomicose (PCM) é causada pelo fungo termo-dimórfico Paracoccidioides …

Melanins are implicated in the pathogenesis of several human diseases, including some
microbial infections. In this study, we analyzed whether the conidia and the yeasts of the …

Paracoccidioidomycosis is the most prevalent systemic endemic mycosis in South America
with most reported cases in Brazil. It is a major cause of disability and death among young …

Most of our knowledge concerning the virulence determinants of pathogenic fungicomes
from the infected host, mainly from animal models and more recently from in vitro studies …

ABSTRACT A nested PCR assay for the detection of Paracoccidioides brasiliensis DNA was
evaluated, using a sequence of the immunogenic gp43 gene as a target. This gene encodes …

Chronic stages of paracoccidioidomycosis (PCM) are characterized by granulomatous
lesions which promote the development of pulmonary fibrosis leading to the loss of …

Patients with paracoccidioidomycosis often present pulmonary fibrosis and exhibit important
respiratory limitations. Based on an already established animal model, the contribution of …