Epigenetics of breast cancer: Biology and clinical implication in the era of precision medicine

B Pasculli, R Barbano, P Parrella - Seminars in cancer biology, 2018 - Elsevier
In the last years, mortality from breast cancer has declined in western countries as a
consequence of a more widespread screening resulting in earlier detection, as well as an …

Nano-drug delivery system: a promising approach against breast cancer

JA Malik, JA Ansari, S Ahmed, A Khan… - Therapeutic …, 2023 - Taylor & Francis
Breast cancer (BC) is among the most frequent malignancies women face around the globe.
Nanotherapeutics are constantly evolving to overcome the limitations of conventional …

[HTML][HTML] Chemotherapy induces ACE2 expression in breast cancer via the ROS-AKT-HIF-1α signaling pathway: a potential prognostic marker for breast cancer …

X Zuo, S Ren, H Zhang, J Tian, R Tian, B Han… - Journal of Translational …, 2022 - Springer
Background Angiotensin-converting enzyme 2 (ACE2) is a key enzyme of the renin-
angiotensin system and a well-known functional receptor for the entry of severe acute …

PD-1, PD-L1, and PD-L2 gene expression and tumor infiltrating lymphocytes in canine melanoma

VB Stevenson, SN Perry, M Todd… - Veterinary …, 2021 - journals.sagepub.com
Melanoma in humans and dogs is considered highly immunogenic; however, the function of
tumor-infiltrating lymphocytes (TILs) is often suppressed in the tumor microenvironment. In …

[HTML][HTML] DoxoDB: A Database for the Expression Analysis of Doxorubicin-Induced LncRNA Genes

R Distefano, M Ilieva, JH Madsen, S Rennie, S Uchida - Non-coding RNA, 2023 - mdpi.com
Cancer and cardiovascular disease are the leading causes of death worldwide. Recent
evidence suggests that these two life-threatening diseases share several features in disease …

[HTML][HTML] Canady helios cold plasma induces breast cancer cell death by oxidation of histone mRNA

X Cheng, SRK Murthy, T Zhuang, L Ly, O Jones… - International Journal of …, 2021 - mdpi.com
Breast cancer is the most common cancer among women worldwide. Its molecular receptor
marker status and mutational subtypes complicate clinical therapies. Cold atmospheric …

[HTML][HTML] Expression and potential prognostic value of histone family gene signature in breast cancer

W Xie, J Zhang, P Zhong, S Qin… - Experimental and …, 2019 - spandidos-publications.com
Breast cancer (BC) is the most common type of malignancy among females worldwide.
Histone modifications, which are the major post-translational modifications, have a …

[HTML][HTML] Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours

C Selli, AK Turnbull, DA Pearce, A Li, A Fernando… - Breast Cancer …, 2019 - Springer
Background The risk of recurrence for endocrine-treated breast cancer patients persists for
many years or even decades following surgery and apparently successful adjuvant therapy …

[HTML][HTML] Proteomic analysis on anti-proliferative and apoptosis effects of curcumin analog, 1, 5-bis (4-hydroxy-3-methyoxyphenyl)-1, 4-pentadiene-3-one-treated …

YQ Lee, P Rajadurai, F Abas, I Othman… - Frontiers in Molecular …, 2021 - frontiersin.org
Curcumin analogs with excellent biological properties have been synthesized to address
and overcome the poor pharmacokinetic profiles of curcumin. This study aims to investigate …

[HTML][HTML] Expand available targets for CAR-T therapy to overcome tumor drug resistance based on the" Evolutionary Traps"

X Wang, P Wang, Y Liao, X Zhao, R Hou, S Li… - Pharmacological …, 2024 - Elsevier
Based on the concept of" Evolutionary Traps", targeting survival essential genes obtained
during tumor drug resistance can effectively eliminate resistant cells. While, it still faces …