Designing photosensitizers for photodynamic therapy: strategies, challenges and promising developments

MJ Garland, CM Cassidy, D Woolfson… - Future medicinal …, 2009 - Taylor & Francis
Photodynamic therapy (PDT) and photodynamic antimicrobial chemotherapy (PACT) are
techniques that combine the effects of visible light irradiation with subsequent biochemical …

Silicon nanoparticles produced by femtosecond laser ablation in water as novel contamination-free photosensitizers

D Rioux, M Laferrière, A Douplik… - Journal of …, 2009 - spiedigitallibrary.org
We report the synthesis of novel inorganic contamination-free photosensitizers based on
colloidal silicon nanoparticles prepared by laser ablation in pure deionized water. We show …

Synthesis and in vitro evaluation of the antitumoral phototherapeutic potential of squaraine cyanine dyes derived from indolenine

E Lima, O Ferreira, VSD Gomes, AO Santos, RE Boto… - Dyes and …, 2019 - Elsevier
In this work several symmetrical indolenine squaraine dyes with different groups positioned
on the four-membered central ring, such as sulfur, barbituric acid, amino and methylamino …

Red and near-infrared absorbing dicyanomethylene squaraine cyanine dyes: photophysicochemical properties and anti-tumor photosensitizing effects

T D. Martins, E Lima, R E. Boto, D Ferreira… - Materials, 2020 - mdpi.com
Photodynamic therapy is a medical modality developed for the treatment of several diseases
of oncological and non-oncological etiology that requires the presence of a photosensitizer …

Study of the efficacy of 5-ALA mediated photodynamic therapy on human rhabdomyosarcoma cell line (RD)

M Atif, M Fakhar-e-Alam, S Firdous… - Laser Physics …, 2010 - iopscience.iop.org
The aim of this study was to investigate the mechanism of cell death by photodynamic
therapy (PDT) in the Rhabdomyosarcoma (RD) cell line. The present study evaluates the …

Luminescence diagnostics of malignant tumors in the IR spectral range using Yb-porphyrin metallocomplexes

AV Ivanov, VD Rumyantseva, KS Shchamkhalov… - Laser Physics, 2010 - Springer
The creation and application of new low-toxic photosensitizers for the luminescence
diagnostics of cancer are considered. The new photosensitizers weakly generate singlet …

Progress in photodynamic therapy on tumors

YY Tian, LL Wang, W Wang - Laser physics, 2008 - Springer
Photodynamic therapy (PDT) is a promising treatment on neoplastic pathologic tissues,
which involves the administration of a photosensitizing agent followed by the exposure of …

Photodynamic activity of indolenine-based aminosquaraine cyanine dyes: Synthesis and in vitro photobiological evaluation

E Lima, O Ferreira, JF Silva, AO Santos, RE Boto… - Dyes and …, 2020 - Elsevier
The synthesis and characterization of several indolenine-based symmetrical squaraine dyes
is herein reported. These compounds, possessing different amine groups bound to the …

Photodynamic efficiency of hypericin compared with chlorin and hematoporphyrin derivatives in HEp-2 and Vero epithelial cell lines

C Bernal, AO Ribeiro, GP Andrade… - … and Photodynamic Therapy, 2015 - Elsevier
Hypericin (HY) is a photoactive aromatic dianthraquinone that is considered a potent
photodynamic agent. In this study, hypericin and two other photosensitizers, a …

The Meta-Substituted Isomer of TMPyP Enables More Effective Photodynamic Bacterial Inactivation than Para-TMPyP In Vitro

S Schulz, S Ziganshyna, N Lippmann, S Glass… - Microorganisms, 2022 - mdpi.com
Porphyrinoid-based photodynamic inactivation (PDI) provides a promising approach to
treating multidrug-resistant infections. However, available agents for PDI still have …