Posterior staphyloma in pathologic myopia

K Ohno-Matsui, JB Jonas - Progress in retinal and eye research, 2019 - Elsevier
A posterior staphyloma is an outpouching of a circumscribed region of the posterior fundus
and has been considered a hallmark of pathologic myopia. Occurring in highly myopic eyes …

Candidate pathways for retina to scleral signaling in refractive eye growth

DM Brown, R Mazade, D Clarkson-Townsend… - Experimental eye …, 2022 - Elsevier
The global prevalence of myopia, or nearsightedness, has increased at an alarming rate
over the last few decades. An eye is myopic if incoming light focuses prior to reaching the …

Animal models in myopia research

F Schaeffel, M Feldkaemper - Clinical and Experimental Optometry, 2015 - Taylor & Francis
Our current understanding of the development of refractive errors, in particular myopia,
would be substantially limited had Wiesel and Raviola not discovered by accident that …

Bruch membrane and the mechanism of myopization: a new theory

JB Jonas, K Ohno-Matsui, WJ Jiang, S Panda-Jonas - Retina, 2017 - journals.lww.com
Background: The process of emmetropization is the adjustment of the length of the optical
axis to the given optical properties of the cornea and lens after the end of the second year of …

[HTML][HTML] Long-wavelength (red) light produces hyperopia in juvenile and adolescent tree shrews

TJ Gawne, AH Ward, TT Norton - Vision Research, 2017 - Elsevier
In infant tree shrews, exposure to narrow-band long-wavelength (red) light, that stimulates
long-wavelength sensitive cones almost exclusively, slows axial elongation and produces …

Axial shortening in myopic children after repeated low-level red-light therapy: post hoc analysis of a randomized trial

W Wang, Y Jiang, Z Zhu, S Zhang, M Xuan… - Ophthalmology and …, 2023 - Springer
Introduction Axial length (AL) elongation in myopia is considered irreversible. We aimed to
systemically report unexpected AL shortening observed in a randomized clinical trial (RCT) …

[HTML][HTML] Tree shrew (Tupaia belangeri) as a novel laboratory disease animal model

J Xiao, R Liu, CS Chen - Zoological research, 2017 - ncbi.nlm.nih.gov
The tree shrew (Tupaia belangeri) is a promising laboratory animal that possesses a closer
genetic relationship to primates than to rodents. In addition, advantages such as small size …

RPE and choroid mechanisms underlying ocular growth and myopia

Y Zhang, CF Wildsoet - Progress in molecular biology and translational …, 2015 - Elsevier
Myopia is the most common type of refractive errors and one of the world's leading causes of
blindness. Visual manipulations in animal models have provided convincing evidence for …

The wavelength composition and temporal modulation of ambient lighting strongly affect refractive development in young tree shrews

TJ Gawne, JT Siegwart Jr, AH Ward… - Experimental eye research, 2017 - Elsevier
Shortly after birth, the eyes of most animals (including humans) are hyperopic because the
short axial length places the retina in front of the focal plane. During postnatal development …

[HTML][HTML] Insight into the molecular genetics of myopia

J Li, Q Zhang - Molecular vision, 2017 - ncbi.nlm.nih.gov
Myopia is the most common cause of visual impairment worldwide. Genetic and
environmental factors contribute to the development of myopia. Studies on the molecular …