Recent medical advances have exploited the ability to address a given disease at the
underlying level of transcription and translation. These treatment paradigms utilize nucleic …

The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Immunotherapy has become a powerful clinical strategy for treating cancer. The number of
immunotherapy drug approvals has been increasing, with numerous treatments in clinical …

Abstract The 2018 Nobel Prize in Physiology or Medicine was awarded to pioneers in the
field of cancer immunotherapy, as the utility of leveraging a patient's coordinated and …

Targeting nanoparticle (NP) carriers to sites of disease is critical for their successful use as
drug delivery systems. Along with optimization of physicochemical properties, researchers …

This Review is an overview of the unique characteristics of cyclodextrin in forming an
inclusion complex via host–guest noncovalent interactions. The modification of cyclodextrin …

Studies on the methods of nanoparticle (NP) synthesis, analysis of their characteristics, and
exploration of new fields of their applications are at the forefront of modern nanotechnology …

Despite regulation of the reactive oxygen species (ROS) level is an intelligent strategy for
cancer therapy, the therapeutic effects of ROS-mediated therapy (including photodynamic …

Artificial intelligence (AI) and nanotechnology are two fields that are instrumental in realizing
the goal of precision medicine—tailoring the best treatment for each cancer patient. Recent …

The therapeutic efficacy of drugs is dependent upon the ability of a drug to reach its target,
and drug penetration into tumors is limited by abnormal vasculature and high interstitial …