Thiazoles, their benzofused systems, and thiazolidinone derivatives: versatile and promising tools to combat antibiotic resistance

S Cascioferro, B Parrino, D Carbone… - Journal of medicinal …, 2020 - ACS Publications
Thiazoles, their benzofused systems, and thiazolidinone derivatives are widely recognized
as nuclei of great value for obtaining molecules with various biological activities, including …

Comprehensive insights into medicinal research on imidazole-based supramolecular complexes

SR Li, YM Tan, L Zhang, CH Zhou - Pharmaceutics, 2023 - mdpi.com
The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents

XC Yang, CF Hu, PL Zhang, S Li, CS Hu, RX Geng… - Bioorganic …, 2022 - Elsevier
A novel type of coumarin thiazoles as unique multi-targeting antimicrobial agents were
developed through four steps including cyclization, nucleophilic substitution and …

Membrane active 7-thiazoxime quinolones as novel DNA binding agents to decrease the genes expression and exert potent anti-methicillin-resistant Staphylococcus …

JP Chen, N Battini, MF Ansari, CH Zhou - European Journal of Medicinal …, 2021 - Elsevier
A novel class of 7-thiazoxime quinolones was developed as potential antimicrobial agents
for the sake of bypassing resistance of quinolones. Biological assays revealed that some …

Thiazole-based analogs as potential antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA) and their SAR elucidation

J Guo, Z Xie, W Ruan, Q Tang, D Qiao, W Zhu - European Journal of …, 2023 - Elsevier
In recent years, the overuse of antibiotics has resulted in the emergence of antibiotic
resistance, which is a serious global health problem. Methicillin-resistant Staphylococcus …

Structure-activity relationship studies of thiazole agents with potential anti methicillin-resistance Staphylococcus aureus (MRSA) activity

J Wang, S Long, Z Liu, KP Rakesh, R Verma… - Process …, 2023 - Elsevier
Due to the increasing resistance of methicillin-resistant Staphylococcus aureus (MRSA) to
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …

Ethylenic conjugated coumarin thiazolidinediones as new efficient antimicrobial modulators against clinical methicillin-resistant Staphylococcus aureus

CF Hu, PL Zhang, YF Sui, JS Lv, MF Ansari, N Battini… - Bioorganic …, 2020 - Elsevier
In an effort for the development of novel antimicrobial agents, ethylenic conjugated coumarin
thiazolidinediones as potential multi-targeting new antimicrobial compounds were …

Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation

LL Wang, N Battini, RRY Bheemanaboina… - European journal of …, 2019 - Elsevier
A series of aminothiazolyl norfloxacin analogues as a new type of potential antimicrobial
agents were synthesized and screened for their antimicrobial activities. Most of the prepared …

Novel carbazole-oxadiazoles as potential Staphylococcus aureus germicides

YP Xie, MF Ansari, SL Zhang, CH Zhou - Pesticide Biochemistry and …, 2021 - Elsevier
Staphylococcus aureus resistance poses nonnegligible threats to the livestock industry. In
light of this, carbazole-oxadiazoles were designed and synthesized for treating S. aureus …

A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes …

LL Wang, N Battini, RRY Bheemanaboina… - European Journal of …, 2019 - Elsevier
This work did a new exploration towards aminothiazolquinolone oximes as potentially multi-
targeting antimicrobial agents. A class of novel hybrids of quinolone, aminothiazole …