Purpose Superagers are older adults presenting excellent memory performance that may
reflect resilience to the conventional pathways of aging. Our contribution aims to shape the …

Alzheimer disease (AD) is the most prevalent form of dementia among elderly people.
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …

Background In preclinical studies, p38⍺ kinase is implicated in Alzheimer's disease (AD)
pathogenesis. In animal models, it mediates impaired synaptic dysfunction in the …

While some individuals age without pathological memory impairments, others develop age‐
associated cognitive diseases. Since changes in cognitive function develop slowly over time …

Lead (Pb) exposure causes immeasurable damage to multiple human systems, particularly
the central nervous system (CNS). In this study, human induced pluripotent stem cells …

Systematic study of tissue-specific function of enhancers and their disease associations is a
major challenge. We present an integrative machine-learning framework, FENRIR, that …

Keep your brain young, healthy, and sharp with this science-driven guide to protecting your
mind from decline by neurosurgeon and CNN chief medical correspondent Sanjay Gupta …

Objectives: To investigate the frequency of exceptional cognition (cognitive super-aging) in
Australian older adults using different published definitions, agreement between definitions …

The p38αMAPK is a serine/threonine protein kinase and a key node in the intracellular
signaling networks that transduce and amplify stress signals into physiological changes. A …

Objective A consistent approach to defining cognitive super‐ageing is needed to increase
the value of research insights that may be gained from studying this population including …