[HTML][HTML] The human papillomavirus (HPV)-related cancer biology: An overview

RP Araldi, TA Sant'Ana, DG Módolo, TC de Melo… - Biomedicine & …, 2018 - Elsevier
Despite the novel diagnostic methods and therapies implemented in oncology, the number
of patients that succumb by the cancer remains high globally. Currently studies point out that …

Reprogramming the tumor microenvironment: tumor-induced immunosuppressive factors paralyze T cells

AA Wu, V Drake, HS Huang, SC Chiu, L Zheng - Oncoimmunology, 2015 - Taylor & Francis
It has become evident that tumor-induced immuno-suppressive factors in the tumor
microenvironment play a major role in suppressing normal functions of effector T cells …

Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer

J Nam, S Son, LJ Ochyl, R Kuai… - Nature …, 2018 - nature.com
Photothermal therapy (PTT) is a promising cancer treatment modality, but PTT generally
requires direct access to the source of light irradiation, thus precluding its utility against …

CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing …

DC Strachan, B Ruffell, Y Oei, MJ Bissell… - …, 2013 - Taylor & Francis
Increased numbers of tumor-infiltrating macrophages correlate with poor disease outcome in
patients affected by several types of cancer, including breast and prostate carcinomas. The …

Effect of human papillomavirus infection on the immune system and its role in the course of cervical cancer

D Song, H Li, H Li, J Dai - Oncology letters, 2015 - spandidos-publications.com
Human papillomavirus (HPV) is widely known as a cause of cervical intraepithelial
neoplasia (CIN) and cervical cancer. The mechanisms involved have been studied by …

Interleukin 10 in the tumor microenvironment: a target for anticancer immunotherapy

T Sato, M Terai, Y Tamura, V Alexeev… - Immunologic …, 2011 - Springer
IL-10 is an immunomodulatory cytokine that is frequently upregulated in various types of
cancer. The biological role of IL-10 in cancer is quite complex; however, the presence of IL …

Immunosuppressive mechanisms of malignant gliomas: parallels at non-CNS sites

P Perng, M Lim - Frontiers in oncology, 2015 - frontiersin.org
The central nervous system (CNS) possesses powerful local and global immunosuppressive
capabilities that modulate unwanted inflammatory reactions in nervous tissue. These same …

The suppressive tumor microenvironment: a challenge in cancer immunotherapy

EA Vasievich, L Huang - Molecular pharmaceutics, 2011 - ACS Publications
In this review, we introduce the changing public perception of vaccines and immunotherapy
in cancer treatments. We discuss the roles that different immunosuppressive cells play in the …

Molecular mechanism of palmitic acid and its derivatives in tumor progression

X Wang, C Zhang, N Bao - Frontiers in oncology, 2023 - frontiersin.org
Palmitic acid (PA) is a saturated fatty acid commonly found in coconut oil and palm oil. It
serves as an energy source for the body and plays a role in the structure and function of cell …

Wound healing‐like immune program facilitates postpartum mammary gland involution and tumor progression

HA Martinson, S Jindal… - … Journal of Cancer, 2015 - Wiley Online Library
Women diagnosed with breast cancer within 5 years postpartum have poor survival rates.
The process of postpartum mammary gland involution, whereby the lactating gland …