The neuronal ceroid lipofuscinoses (NCLs) are clinically and genetically heterogeneous
neurodegenerative disorders. Most are autosomal recessively inherited. Clinical features …

The fatal, primarily childhood neurodegenerative disorders, neuronal ceroid lipofuscinoses
(NCLs), are currently associated with mutations in 13 genes. The protein products of these …

Neuronal ceroid lipofuscinoses (NCL) comprise a group of inherited lysosomal disorders
with variable age of onset, characterized by lysosomal accumulation of autofluorescent …

Despite the identification of a large number of disease-causing genes in recent years, it is
still unclear what disease mechanisms operate in the neuronal ceroid lipofuscinoses (NCLs …

Abstract Neuronal ceroid lipofuscinoses (NCLs; Batten disease) are collectively the most
frequent autosomal-recessive neurodegenerative disease of childhood, but the underlying …

Neuronal ceroid lipofuscinoses (NCLs; also known collectively as Batten Disease) are a
family of autosomal recessive lysosomal storage disorders. Mutations in as many as 13 …

The neuronal ceroid lipofuscinoses (NCL) are heterogeneous neurodegenerative disorders
with typical autofluorescence material stored in tissues. Ten clinical NCL forms and eight …

Neuronal ceroid lipofuscinoses (NCLs) are a group of inherited childhood
neurodegenerative disorders. In addition to the accumulation of auto‐fluorescent storage …

Biomarkers are extremely important in the case of multisystemic diseases, such as
lysosomal storage disorders (LSDs), which are often difficult to assess in clinical practice …

A 23-month-old neutered male dog of unknown ancestry presented with a history of
progressive neurological signs that included anxiety, cognitive impairment, tremors, seizure …