Research in developmental biology has been recently enriched by a multitude of in vitro
models recapitulating key milestones of mammalian embryogenesis. These models obviate …

Implantation of the conceptus into the uterus is absolutely essential for successful embryo
development. In humans, our understanding of this process has remained rudimentary …

Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our
understanding of the complex interactions among their respective disease pathways …

STUDY QUESTION Can we reconstitute physiologically relevant 3-dimensional (3D)
microengineered endometrium in-vitro model? SUMMARY ANSWER Our representative …

Extracellular vesicles (EVs) are small vesicles ranging from 20–200 nm to 10 μm in diameter
that are discharged and taken in by many different types of cells. Depending on the nature …

The herbicide market is growing rapidly, as weed control is a significant challenge in
agriculture. Many studies have reported the toxicity of herbicides to non-target organisms …

It is fascinating that the amnion and serosa/chorion, two extraembryonic (EE) tissues that are
characteristic of the amniote vertebrates (mammals, birds and reptiles), have also …

Endometrial receptivity and embryo implantation processes are a major point of pregnancy
failure in many mammalian species, including humans. Although reproductive biology in …

Evolutionary changes in the anatomy and physiology of the female reproductive system
underlie the origins and diversification of pregnancy in Eutherian ('placental') mammals. This …

Embryogenesis is a complex multi-stage process regulated by various signaling molecules
including pineal and extrapineal melatonin (MT). Extrapineal MT is found in the placenta …