Hedonic eating and the “delicious circle”: from lipid-derived mediators to brain dopamine and back

R Coccurello, M Maccarrone - Frontiers in neuroscience, 2018 - frontiersin.org
Palatable food can be seductive and hedonic eating can become irresistible beyond hunger
and negative consequences. This is witnessed by the subtle equilibrium between eating to …

Endocannabinoid signaling and food addiction

C D'Addario, MVM Di Bonaventura, M Pucci… - Neuroscience & …, 2014 - Elsevier
Overeating, frequently linked to an increasing incidence of overweight and obesity, has
become epidemic and one of the leading global health problems. To explain the …

Endocannabinoids and the gut-brain control of food intake and obesity

NV DiPatrizio - Nutrients, 2021 - mdpi.com
Gut-brain signaling controls food intake and energy homeostasis, and its activity is thought
to be dysregulated in obesity. We will explore new studies that suggest the …

The endocannabinoid system and eating behaviours: a review of the current state of the evidence

N Aguilera Vasquez, DE Nielsen - Current Nutrition Reports, 2022 - Springer
Abstract Purpose of the Review The endocannabinoid system (ENS) has emerged as an
important factor in food intake and may have implications for nutrition research. The …

Fatty acid modulation of the endocannabinoid system and the effect on food intake and metabolism

SS Naughton, ML Mathai, DH Hryciw… - International journal …, 2013 - Wiley Online Library
Endocannabinoids and their G‐protein coupled receptors (GPCR) are a current research
focus in the area of obesity due to the system's role in food intake and glucose and lipid …

Hypothalamic endocannabinoids in obesity: an old story with new challenges

C Miralpeix, AC Reguera, A Fosch, S Zagmutt… - Cellular and Molecular …, 2021 - Springer
The crucial role of the hypothalamus in the pathogenesis of obesity is widely recognized,
while the precise molecular and cellular mechanisms involved are the focus of intense …

The role of astrocytes in the hypothalamic response and adaptation to metabolic signals

JA Chowen, P Argente-Arizón, A Freire-Regatillo… - Progress in …, 2016 - Elsevier
The hypothalamus is crucial in the regulation of homeostatic functions in mammals, with the
disruption of hypothalamic circuits contributing to chronic conditions such as obesity …

Obesity as a Condition determined by Food Addiction: should Brain Endocannabinoid System alterations be the cause and its Modulation the Solution?

M de Ceglia, J Decara, S Gaetani… - Pharmaceuticals, 2021 - mdpi.com
Obesity is a complex disorder, and the number of people affected is growing every day. In
recent years, research has confirmed the hypothesis that food addiction is a determining …

Cannabinoid CB1 Receptors in the Intestinal Epithelium Are Required for Acute Western-Diet Preferences in Mice

B Avalos, DA Argueta, PA Perez, M Wiley, C Wood… - Nutrients, 2020 - mdpi.com
The endocannabinoid system plays an important role in the intake of palatable food. For
example, endocannabinoid signaling in the upper small-intestinal epithelium is increased (i) …

Effects of bingeing on fat during adolescence on the reinforcing effects of cocaine in adult male mice

MC Blanco-Gandía, L Cantacorps… - …, 2017 - Elsevier
Binge eating is a specific form of overeating characterized by intermittent excessive eating.
In addition to altering the neurobiological reward system, several studies have highlighted …