High mobility group A 2 (HMGA2) is a protein that modulates the structure of chromatin in the
nucleus. Importantly, aberrant expression of HMGA2 occurs during carcinogenesis, and this …

The Notch gene, a highly evolutionarily conserved gene, was discovered approximately 110
years ago and has been found to play a crucial role in the development of multicellular …

Cancer is a multifactorial process associated with changes in signaling pathways leading to
cell cycle variations and gene expression. The transient receptor potential melastatin 8 …

The long noncoding RNA (lncRNA)/Wingless (Wnt) axis is often dysregulated in digestive
system tumors impacting critical cellular processes. Abnormal expression of specific Wnt …

Simple Summary This manuscript focuses on the complex relationships between autophagy
and epithelial mesenchymal transition (EMT) in cancer. Autophagy, a cellular degradation …

The emergence of RNA modifications has recently been considered as critical post-
transcriptional regulations which governed gene expression. N 6-methyladenosine (m 6 A) …

Cancer is a group of diseases marked by unchecked cell proliferation and the ability for the
disease to metastasize to different body areas. Enhancements in treatment and early …

Notch signaling, renowned for its role in regulating cell fate, organ development, and tissue
homeostasis across metazoans, is highly conserved throughout evolution. The Notch …

Abstract Nuclear Dbf2-related kinase 1 (NDR1) is a nuclear Dbf2-related (NDR) protein
kinase family member, which regulates cell functions and participates in cell proliferation …

The combined diagnostic imaging, chemotherapy, and gene therapy based on DNA
nanocarriers can reduce the toxic side effects and overcome multidrug resistance (MDR). In …