The mammalian hippocampal formation contains several distinct populations of neurons
involved in representing self-position and orientation. These neurons, which include place …

In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …

Throughout development, the brain transits from early highly synchronous activity patterns to
a mature state with sparse and decorrelated neural activity, yet the mechanisms underlying …

An essential step toward understanding brain function is to establish a structural framework
with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and …

Spatial molecular profiling of complex tissues is essential to investigate cellular function in
physiological and pathological states. However, methods for molecular analysis of large …

Over the last ten years, developments in whole-brain microscopy now allow for high-
resolution imaging of intact brains of small animals such as mice. These complex images …

Central oscillators are primordial neural circuits that generate and control rhythmic
movements,. Mechanistic understanding of these circuits requires genetic identification of …

Psilocybin is a psychedelic with therapeutic potential. While there is growing evidence that
psilocybin exerts its beneficial effects through enhancing neural plasticity, the exact brain …

Adaptive behaviour necessitates the formation of memories for fearful events, but also that
these memories can be extinguished. Effective extinction prevents excessive and persistent …

Perineuronal nets (PNNs) surround specific neurons in the brain and are involved in various
forms of plasticity and clinical conditions. However, our understanding of the PNN role in …