Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine

M Brown, J Li, C Moraes, M Tabrizian, NYK Li-Jessen - Biomaterials, 2022 - Elsevier
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

Decellularized extracellular matrix-based bioinks for engineering tissue-and organ-specific microenvironments

BS Kim, S Das, J Jang, DW Cho - Chemical reviews, 2020 - ACS Publications
Biomaterials-based biofabrication methods have gained much attention in recent years.
Among them, 3D cell printing is a pioneering technology to facilitate the recapitulation of …

Light‐activated decellularized extracellular matrix‐based bioinks for volumetric tissue analogs at the centimeter scale

H Kim, B Kang, X Cui, SH Lee, K Lee… - Advanced Functional …, 2021 - Wiley Online Library
Tissue engineering requires not only tissue‐specific functionality but also a realistic scale.
Decellularized extracellular matrix (dECM) is presently applied to the extrusion‐based 3D …

Designing scaffolds for corneal regeneration

M Ahearne, J Fernández‐Pérez… - Advanced Functional …, 2020 - Wiley Online Library
Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Hydrogels as emerging materials for cornea wound healing

S Khosravimelal, M Mobaraki, S Eftekhari, M Ahearne… - Small, 2021 - Wiley Online Library
Hydrogel biomaterials have many favorable characteristics including tuneable mechanical
behavior, cytocompatibility, optical properties suitable for regeneration and restoration of the …

Porcine lung-derived extracellular matrix hydrogel properties are dependent on pepsin digestion time

RA Pouliot, BM Young, PA Link, HE Park… - … Engineering Part C …, 2020 - liebertpub.com
Hydrogels derived from decellularized lungs are promising materials for tissue engineering
in the development of clinical therapies and for modeling the lung extracellular matrix (ECM) …

[HTML][HTML] Decellularized Disc Hydrogels for hBMSCs tissue-specific differentiation and tissue regeneration

Y Peng, X Qing, H Lin, D Huang, J Li, S Tian, S Liu… - Bioactive materials, 2021 - Elsevier
Tissue specificity, a key factor in the decellularized tissue matrix (DTM), has shown bioactive
functionalities in tuning cell fate—eg, the differentiation of mesenchymal stem cells. Notably …

A light‐curable and tunable extracellular matrix hydrogel for in situ suture‐free corneal repair

G Yazdanpanah, X Shen, T Nguyen… - Advanced functional …, 2022 - Wiley Online Library
Corneal injuries are a major cause of blindness worldwide. To restore corneal integrity and
clarity, there is a need for regenerative biointegrating materials for in situ repair and …

Mechanical properties of bioengineered corneal stroma

N Formisano, C van der Putten, R Grant… - Advanced …, 2021 - Wiley Online Library
For the majority of patients with severe corneal injury or disease, corneal transplantation is
the only suitable treatment option. Unfortunately, the demand for donor corneas greatly …

Decellularized extracellular matrix-based composite scaffolds for tissue engineering and regenerative medicine

P Xu, RK Kankala, S Wang… - Regenerative Biomaterials, 2024 - academic.oup.com
Despite the considerable advancements in fabricating polymeric-based scaffolds for tissue
engineering, the clinical transformation of these scaffolds remained a big challenge because …