Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …

All living organisms can make lipid droplets (LDs), intracellular oil-in-water droplets,
surrounded by a phospholipid and protein monolayer. LDs are at the nexus of cellular lipid …

Mycobacterium tuberculosis (Mtb) cultured axenically without detergent forms biofilm-like
cords, a clinical identifier of virulence. In lung-on-chip (LoC) and mouse models, cords in …

The pathogen Mycobacterium tuberculosis (Mtb), causing tuberculosis disease, features an
extraordinary thick cell envelope, rich in Mtb-specific lipids, glycolipids, and glycans. These …

Necrosis of macrophages in the granuloma, the hallmark immunological structure of
tuberculosis, is a major pathogenic event that increases host susceptibility. Through a …

An estimated one-third of tuberculosis (TB) cases go undiagnosed or unreported. Sputum
samples, widely used for TB diagnosis, are inefficient at detecting infection in children and …

Unlike typical Gram-positive bacteria, the cell envelope of mycobacteria is unique and
composed of a mycobacterial outer membrane, also known as the mycomembrane, a …

Bilayered membranes separate cells from their surroundings and form boundaries between
intracellular organelles and the cytosol. Gated transport of solutes across membranes …

Mycobacterium tuberculosis (Mtb) is a very successful pathogen, strictly adapted to humans
and the cause of tuberculosis. Its success is associated with its ability to inhibit host cell …

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a
leading cause of death due to infection in humans. To more effectively combat this …