Role of cholesterol in the function and organization of G-protein coupled receptors

TJ Pucadyil, A Chattopadhyay - Progress in lipid research, 2006 - Elsevier
Cholesterol is an essential component of eukaryotic membranes and plays a crucial role in
membrane organization, dynamics and function. The modulatory role of cholesterol in the …

The Serotonin 1A A Receptor: A Representative Member of the Serotonin Receptor Family

TJ Pucadyil, S Kalipatnapu… - Cellular and molecular …, 2005 - Springer
Serotonin is an intrinsically fluorescent biogenic amine that acts as a neurotransmitter and is
found in a wide variety of sites in the central and peripheral nervous system. Serotonergic …

Influence of surfactant and electrolyte concentrations on surfactant Adsorption and foaming characteristics

N Yekeen, MA Manan, AK Idris, AM Samin - Journal of Petroleum Science …, 2017 - Elsevier
Surfactant adsorption and foaming characteristics are influenced by surfactant concentration
and presence of inorganic electrolytes. Hence, it should be possible to optimize the …

Determination of the critical micelle concentration of neutral and ionic surfactants with fluorometry, conductometry, and surface tension—a method comparison

N Scholz, T Behnke, U Resch-Genger - Journal of fluorescence, 2018 - Springer
Micelles are of increasing importance as versatile carriers for hydrophobic substances and
nanoprobes for a wide range of pharmaceutical, diagnostic, medical, and therapeutic …

Structure of translation factor elF4E bound to m7GDP and interaction with 4E-binding protein

H Matsuo, H Li, AM McGuire, CM Fletcher… - Nature structural …, 1997 - nature.com
Abstract elF4E, the mRNA cap binding protein, is a master switch that controls eukaryotic
translation. To be active, it must bind elF4G and form the elF4F complex, which also contains …

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain

JM Kefauver, M Hakala, L Zou, J Alba, J Espadas… - Nature, 2024 - nature.com
Biological membranes are partitioned into functional zones termed membrane
microdomains, which contain specific lipids and proteins,–. The composition and …

[HTML][HTML] Cholesterol modulates ligand binding and G-protein coupling to serotonin1A receptors from bovine hippocampus

TJ Pucadyil, A Chattopadhyay - Biochimica et Biophysica Acta (BBA) …, 2004 - Elsevier
The serotonin1A (5-HT1A) receptor is an important member of the superfamily of seven-
transmembrane domain G-protein-coupled receptors. We have examined the modulatory …

Effects of surfactant and electrolyte concentrations on bubble formation and stabilization

Q Xu, M Nakajima, S Ichikawa, N Nakamura… - Journal of Colloid and …, 2009 - Elsevier
As interest in the application of microbubbles grows, it is becoming increasingly important to
understand the factors affecting their formation and properties in order to effectively generate …

Purification of a jojoba embryo fatty acyl-coenzyme A reductase and expression of its cDNA in high erucic acid rapeseed

JG Metz, MR Pollard, L Anderson, TR Hayes… - Plant …, 2000 - academic.oup.com
The jojoba (Simmondsia chinensis) plant produces esters of long-chain alcohols and fatty
acids (waxes) as a seed lipid energy reserve. This is in contrast to the triglycerides found in …

Structural prerequisites for G-protein activation by the neurotensin receptor

BE Krumm, JF White, P Shah, R Grisshammer - Nature communications, 2015 - nature.com
We previously determined the structure of neurotensin receptor NTSR1 in an active-like
conformation with six thermostabilizing mutations bound to the peptide agonist neurotensin …