The immune system has the daunting task of distinguishing between self and non-self. The
mucosal immune system, present along the respiratory, gastrointestinal and genitourinary …

Oral tolerance means a diminished immune response to previously fed antigens. Repeated
oral administrations of type II collagen (CII) induce oral tolerance and inhibit the …

Objective: The aim of this randomized controlled study was to evaluate the efficacy of oral
native type II collagen treatment on the symptoms and biological markers of cartilage …

Background: Early knee osteoarthritis (OA) treatment is multimodal, with physical therapy
and pharmacotherapy commonly used. Although popular, oral supplements like …

The purpose of this paper was to extract and characterize type II collagen of sturgeon
cartilage (SC-CII), and to explore the effects of taking SC-CII orally on rheumatoid arthritis …

Oral administration of an antigen can result in local and systemic priming or tolerance and
the basis of this dichotomy is poorly understood. The intestinal microenvironment, and …

Rheumatoid arthritis is a chronic disorder for which there is no known cure. Concentrating
on specific elements of the abnormal immune response that characterizes the disease …

Immunotherapy of rheumatoid arthritis (RA) using oral-dosed native chicken or bovine type II
collagen (nCII) to induce specific immune tolerance is an attractive strategy. However, the …

Fonksiyonel bir bileşen olan kolajen hidrolizatı, kolajenin enzimatik hidrolize uğraması
sonucunda oluşan çoğunlukla içecek sektöründe kemik ve cilt sağlığını düzenlemek …

Chitosan is a mucoadhesive polysaccharide that promotes the transmucosal absorption of
peptides and proteins. At mucosal sites chitosan exhibits immunomodulatory activities and …