Advances in pharmacological activities of terpenoids

W Yang, X Chen, Y Li, S Guo… - Natural Product …, 2020 - journals.sagepub.com
Terpenoids, the most abundant compounds in natural products, are a set of important
secondary metabolites in plants with diverse structures. Terpenoids play key roles in plant …

Advances in schistosomiasis drug discovery based on natural products.

FL Mtemeli, J Ndlovu, G Mugumbate, T Makwikwi… - All Life, 2022 - Taylor & Francis
Schistosomiasis is a neglected tropical disease affecting over 250 million people worldwide.
The disease is the second most prevalent neglected tropical disease after malaria …

Therapeutic efficacy of carvacrol-loaded nanoemulsion in a mouse model of schistosomiasis

ES Xavier, RL de Souza, VC Rodrigues… - Frontiers in …, 2022 - frontiersin.org
Since praziquantel is the only drug available to treat schistosomiasis, a neglected parasitic
disease that affects more than 240 million people worldwide, there is an urgent demand for …

In Vitro and In Vivo Effectiveness of Carvacrol, Thymol and Linalool against Leishmania infantum

MR Youssefi, E Moghaddas, MA Tabari… - Molecules, 2019 - mdpi.com
Background: One of the most important causative agents of visceral leishmaniasis (VL) is
Leishmania infantum, which is mainly spread by Phlebotomus and Lutzomyia sandflies in …

Brazilian red propolis exhibits antiparasitic properties in vitro and reduces worm burden and egg production in an mouse model harboring either early or chronic …

MP Silva, TM Silva, AC Mengarda, MC Salvadori… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Propolis has been used in folk medicine for thousands of
years and, in the past few decades, it has attracted renewed interest. Although propolis has …

Antiparasitic activity of piplartine (piperlongumine) in a mouse model of schistosomiasis

AC Mengarda, PS Mendonca, CS Morais, RM Cogo… - Acta tropica, 2020 - Elsevier
Schistosomiasis is one of the most important parasitic infections in terms of its negative
effects on public health and economics. Since praziquantel is currently the only drug …

Antiparasitic activity of nerolidol in a mouse model of schistosomiasis

MP Silva, RN de Oliveira, AC Mengarda… - International Journal of …, 2017 - Elsevier
Schistosomiasis is a major public health problem worldwide, especially in poor
communities. Since praziquantel is currently the only drug available to treat schistosomiasis …

Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasis

EM Lago, MP Silva, TG Queiroz, SF Mazloum… - …, 2019 - thelancet.com
Background Treatment and control of schistosomiasis, one of the most insidious and serious
parasitic diseases, depend almost entirely on a single drug, praziquantel. Since the funding …

Neolignans isolated from Saururus cernuus L. (Saururaceae) exhibit efficacy against Schistosoma mansoni

JR Brito, P Wilairatana, DB Roquini, BC Parra… - Scientific Reports, 2022 - nature.com
Schistosomiasis, a parasitic disease caused by the blood fluke of the genus Schistosoma,
affects over 230 million people, especially in developing countries. Despite the significant …

Cytotoxic and Antioxidant Properties of Natural Bioactive Monoterpenes Nerol, Estragole, and 3, 7‐Dimethyl‐1‐Octanol

ML Coêlho, MT Islam… - Advances in …, 2022 - Wiley Online Library
The therapeutic potential of medicinal plants is noted because of the presence of varieties of
biochemicals. The monoterpenes, like nerol, estragole, and 3, 7‐dimethyl‐1‐octanol, have …