IPNA clinical practice recommendations for the diagnosis and management of children with steroid-sensitive nephrotic syndrome

A Trautmann, O Boyer, E Hodson, A Bagga… - Pediatric …, 2023 - Springer
Idiopathic nephrotic syndrome is the most frequent pediatric glomerular disease, affecting
from 1.15 to 16.9 per 100,000 children per year globally. It is characterized by massive …

Corticosteroid therapy for nephrotic syndrome in children

D Hahn, SM Samuel, NS Willis… - … of systematic reviews, 2024 - cochranelibrary.com
Background In nephrotic syndrome, protein leaks from the blood into the urine through the
glomeruli, resulting in hypoproteinaemia and generalised oedema. While most children with …

KDIGO 2021 clinical practice guideline for the management of glomerular diseases

BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

Steroid sensitive nephrotic syndrome: revised guidelines

A Sinha, A Bagga, S Banerjee, K Mishra… - Asian Journal of …, 2021 - journals.lww.com
Objective: To frame revised guidelines on diagnosis, evaluation, management, and
supportive care of patients with the illness. Process: The guidelines combine evidence …

Childhood nephrotic syndrome

M Vivarelli, K Gibson, A Sinha, O Boyer - The Lancet, 2023 - thelancet.com
Idiopathic nephrotic syndrome is the most common glomerular disease in children.
Corticosteroids are the cornerstone of its treatment, and steroid response is the main …

Evaluation of daily low-dose prednisolone during upper respiratory tract infection to prevent relapse in children with relapsing steroid-sensitive nephrotic syndrome …

MT Christian, NJA Webb, S Mehta, RL Woolley… - JAMA …, 2022 - jamanetwork.com
Importance In children with corticosteroid-sensitive nephrotic syndrome, many relapses are
triggered by upper respiratory tract infections. Four small studies found that administration of …

KDOQI US commentary on the 2021 KDIGO clinical practice guideline for the management of glomerular diseases

LH Beck Jr, I Ayoub, D Caster, MJ Choi, J Cobb… - American Journal of …, 2023 - Elsevier
The KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases
represents the first update to this set of recommendations since the initial set of KDIGO …

Pediatric idiopathic steroid-sensitive nephrotic syndrome: diagnosis and therapy—short version of the updated German best practice guideline (S2e)—AWMF register …

R Ehren, MR Benz, PT Brinkkötter, J Dötsch… - Pediatric …, 2021 - Springer
Idiopathic nephrotic syndrome is the most frequent glomerular disease in children in most
parts of the world. Children with steroid-sensitive nephrotic syndrome (SSNS) generally …

Molecular mechanisms of proteinuria in minimal change disease

S Purohit, F Piani, FA Ordoñez… - Frontiers in …, 2021 - frontiersin.org
Minimal change disease (MCD) is the most common type of idiopathic nephrotic syndrome
in childhood and represents about 15% cases in adults. It is characterized by massive …

Current understanding of nephrotic syndrome in children

TK Mattoo, S Sanjad - Pediatric Clinics, 2022 - pediatric.theclinics.com
Nephrotic syndrome (NS) in children is characterized by the presence of significant
proteinuria, hypoalbuminemia, and edema. About 90% of the cases between 1 and 10 years …