The role of IGF2BP2, an m6A reader gene, in human metabolic diseases and cancers

J Wang, L Chen, P Qiang - Cancer cell international, 2021 - Springer
The human insulin-like growth factor 2 (IGF2) mRNA binding proteins 2 (IGF2BP2/IMP2) is
an RNA-binding protein that regulates multiple biological processes. Previously, IGF2BP2 …

Diabetes in Asia: epidemiology, risk factors, and pathophysiology

JCN Chan, V Malik, W Jia, T Kadowaki, CS Yajnik… - Jama, 2009 - jamanetwork.com
Context With increasing globalization and East-West exchanges, the increasing epidemic of
type 2 diabetes in Asia has far-reaching public health and socioeconomic implications …

Globalization of diabetes: the role of diet, lifestyle, and genes

FB Hu - Diabetes care, 2011 - Am Diabetes Assoc
Type 2 diabetes is a global public health crisis that threatens the economies of all nations,
particularly developing countries. Fueled by rapid urbanization, nutrition transition, and …

Diabetes in asia

A Ramachandran, RCW Ma, C Snehalatha - The Lancet, 2010 - thelancet.com
Prevalence of type 2 diabetes has rapidly increased in native and migrant Asian
populations. Diabetes develops at a younger age in Asian populations than in white …

Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study

L Kong, J Zhu, W Han, X Jiang, M Xu, Y Zhao, Q Dong… - Acta …, 2011 - Springer
To explore the clinical significance of seven diabetes-related serum microRNAs (miR-9, miR-
29a, miR-30d, miR34a, miR-124a, miR146a and miR375) during the pathogenesis of type 2 …

The worldwide diabetes epidemic

DW Lam, D LeRoith - Current Opinion in Endocrinology, Diabetes …, 2012 - journals.lww.com
Diabetes promises to become an even larger public health issue with significant social and
economic burden with clinical practice and public health policy implications. Further …

Zinc and diabetes—clinical links and molecular mechanisms

J Jansen, W Karges, L Rink - The Journal of nutritional biochemistry, 2009 - Elsevier
Zinc is an essential trace element crucial for the function of more than 300 enzymes and it is
important for cellular processes like cell division and apoptosis. Hence, the concentration of …

A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese

FJ Tsai, CF Yang, CC Chen, LM Chuang, CH Lu… - PLoS …, 2010 - journals.plos.org
To investigate the underlying mechanisms of T2D pathogenesis, we looked for diabetes
susceptibility genes that increase the risk of type 2 diabetes (T2D) in a Han Chinese …

The roles of insulin‐like growth factor 2 mRNA‐binding protein 2 in cancer and cancer stem cells

J Cao, Q Mu, H Huang - Stem cells international, 2018 - Wiley Online Library
RNA‐binding proteins (RBPs) mediate the localization, stability, and translation of the target
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …

Genome-wide association studies: potential next steps on a genetic journey

MI McCarthy, JN Hirschhorn - Human molecular genetics, 2008 - academic.oup.com
Genome-wide association studies have successfully identified numerous loci at which
common variants influence disease risk or quantitative traits. Despite these successes, the …