Prognostic and therapeutic implications of microvascular invasion in hepatocellular carcinoma

DJ Erstad, KK Tanabe - Annals of surgical oncology, 2019 - Springer
Hepatocellular carcinoma (HCC) is a morbid condition for which surgical and ablative
therapy are the only options for cure. Nonetheless, over half of patients treated with an R0 …

Radiogenomics: bridging imaging and genomics

Z Bodalal, S Trebeschi, TDL Nguyen-Kim, W Schats… - Abdominal …, 2019 - Springer
From diagnostics to prognosis to response prediction, new applications for radiomics are
rapidly being developed. One of the fastest evolving branches involves linking imaging …

Postoperative adjuvant hepatic arterial infusion chemotherapy with FOLFOX in hepatocellular carcinoma with microvascular invasion: a multicenter, phase III …

SH Li, J Mei, Y Cheng, Q Li, QX Wang… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To report the efficacy and safety of postoperative adjuvant hepatic arterial
infusion chemotherapy (HAIC) with 5-fluorouracil and oxaliplatin (FOLFOX) in hepatocellular …

Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy

Z Li, R Pai, S Gupta, J Currenti, W Guo… - Nature Cancer, 2024 - nature.com
Onco-fetal reprogramming of the tumor ecosystem induces fetal developmental signatures in
the tumor microenvironment, leading to immunosuppressive features. Here, we employed …

Effect of microvascular invasion risk on early recurrence of hepatocellular carcinoma after surgery and radiofrequency ablation

S Lee, TW Kang, KD Song, MW Lee, H Rhim… - Annals of …, 2021 - journals.lww.com
Objective: We compared surgical resection (SR) and radiofrequency ablation (RFA) as first-
line treatment in patients with hepatocellular carcinoma (HCC) based on the risk of …

Nomogram for preoperative estimation of microvascular invasion risk in hepatitis B virus–related hepatocellular carcinoma within the milan criteria

Z Lei, J Li, D Wu, Y Xia, Q Wang, A Si, K Wang… - JAMA …, 2016 - jamanetwork.com
Importance The presence of microvascular invasion (MVI) decreases surgical outcomes of
hepatocellular carcinoma (HCC). An accurate preoperative prediction of MVI can help …

Systematic review: radiomics for the diagnosis and prognosis of hepatocellular carcinoma

E Harding‐Theobald, J Louissaint… - Alimentary …, 2021 - Wiley Online Library
Background Advances in imaging technology have the potential to transform the early
diagnosis and treatment of hepatocellular carcinoma (HCC) through quantitative image …

Preoperative identification of microvascular invasion in hepatocellular carcinoma by XGBoost and deep learning

YQ Jiang, SE Cao, S Cao, JN Chen, GY Wang… - Journal of cancer …, 2021 - Springer
Purpose Microvascular invasion (MVI) is a valuable predictor of survival in hepatocellular
carcinoma (HCC) patients. This study developed predictive models using eXtreme Gradient …

A systematic review of microvascular invasion in hepatocellular carcinoma: diagnostic and prognostic variability

M Rodriguez-Peralvarez, TV Luong… - Annals of surgical …, 2013 - Springer
Selected patients with hepatocellular carcinoma are candidates to receive potentially
curative treatments, such as hepatic resection or liver transplantation, but nevertheless there …

Can current preoperative imaging be used to detect microvascular invasion of hepatocellular carcinoma?

M Renzulli, S Brocchi, A Cucchetti, F Mazzotti… - Radiology, 2016 - pubs.rsna.org
Purpose To determine the accuracy of imaging features, such as tumor dimension,
multinodularity, nonsmooth tumor margins, peritumoral enhancement, and radiogenomic …