Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …

Alzheimer's disease (AD) is behaviorally identified by progressive memory impairment and
pathologically characterized by the triad of β-amyloid plaques, neurofibrillary tangles, and …

There are many differences in arterial diseases between men and women, including
prevalence, clinical manifestations, treatments, and prognosis. The new policy of the …

Low and oscillatory wall shear stress is widely assumed to play a key role in the initiation
and development of atherosclerosis. Indeed, some studies have relied on the low shear …

Atherosclerotic plaques impair vascular function and can lead to arterial obstruction and
tissue ischaemia. Rupture of an atherosclerotic plaque within a coronary artery can result in …

Objective: HDL (high-density lipoprotein) infusion reduces atherosclerosis in animal models
and is being evaluated as a treatment in humans. Studies have shown either anti-or …

Subtle clotting that occurs on the luminal surface of atherosclerotic plaques presents a novel
target for nanoparticle-based diagnostics and therapeutics. We have developed modular …

Collagens constitute a major portion of the extracellular matrix in the atherosclerotic plaque,
where they contribute to the strength and integrity of the fibrous cap, and also modulate …

Galectin-3 has been increasingly recognized as an important modulator of several biological
functions, by interacting with several molecules inside and outside the cell, and an emerging …

Objective: MR (mineralocorticoid receptor) activation is associated with cardiovascular
ischemia in humans. This study explores the role of the MR in atherosclerotic mice of both …