[HTML][HTML] Abundant proteins in platelet-rich fibrin and their potential contribution to wound healing: An explorative proteomics study and review of the literature

E Yaprak, M Kasap, G Akpinar, EE Islek… - Journal of dental …, 2018 - Elsevier
Background/purpose It is well-known that diverse types of blood proteins contribute to
healing process via different mechanisms. Presence and potential involvements of blood …

PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons

H Bogetofte, P Jensen, M Ryding, SI Schmidt… - Frontiers in cellular …, 2019 - frontiersin.org
The protein parkin, encoded by the PARK2 gene, is vital for mitochondrial homeostasis, and
although it has been implicated in Parkinson's disease (PD), the disease mechanisms …

Proteomic studies associated with Parkinson's disease

M Kasap, G Akpinar, A Kanli - Expert review of proteomics, 2017 - Taylor & Francis
Introduction: Parkinson's disease (PD) is an insidious disorder affecting more than 1–2% of
the population over the age of 65. Understanding the etiology of PD may create …

Neurodegenerative disorders: From clinicopathology convergence to systems biology divergence

M Fasano, T Alberio - Handbook of Clinical Neurology, 2023 - Elsevier
Neurodegenerative diseases are multifactorial. This means that several genetic, epigenetic,
and environmental factors contribute to their emergence. Therefore, for the future …

A systems biology-led insight into the role of the proteome in neurodegenerative diseases

M Fasano, C Monti, T Alberio - Expert review of proteomics, 2016 - Taylor & Francis
Introduction: Multifactorial disorders are the result of nonlinear interactions of several factors;
therefore, a reductionist approach does not appear to be appropriate. Proteomics is a global …

Quantitative proteomics in A30P* A53T α-synuclein transgenic mice reveals upregulation of Sel1l

J Yan, P Zhang, F Jiao, Q Wang, F He, Q Zhang… - PloS one, 2017 - journals.plos.org
α-Synuclein is an abundantly expressed neuronal protein that is at the center of focus in
understanding a group of neurodegenerative disorders called synucleinopathies, which are …

Proteomic analysis of talazoparib resistance in triple‐negative breast cancer cells

G Guney Eskiler, S Yanar, G Akpinar… - Journal of biochemical …, 2021 - Wiley Online Library
Talazoparib (TAL) has been effectively used for the treatment of gBRCA1/2‐mutated HER2‐
negative metastatic breast cancer. However, acquired resistance to TAL remains a major …

Investigation of the involvement of parkin in parkinson's disease and cancer by monitoring the changes in sh-sy5y cells at the nuclear proteome level

A Ayimugu, M Sarihan, M Kasap… - Anticancer Research, 2020 - ar.iiarjournals.org
Background/Aim: During the last two decades, Parkinson's disease (PD)-associated genes
have been associated with cancer; however, a shared pathogenic mechanism has yet to be …

Embryonic poly (A)-binding protein interacts with translation-related proteins and undergoes phosphorylation on the serine, threonine, and tyrosine residues in the …

S Ozturk, EG Kosebent, G Talibova, Y Bilmez… - Journal of Assisted …, 2023 - Springer
Expression of the embryonic poly (A)-binding protein (EPAB) in frog, mouse, and human
oocytes and early-stage embryos is maintained at high levels until embryonic genome …

Comparative proteomics analysis of four commonly used methods for identification of novel plasma membrane proteins

KK Yoneten, M Kasap, G Akpinar, A Kanli… - The Journal of Membrane …, 2019 - Springer
Plasma membrane proteins perform a variety of important tasks in the cells. These tasks can
be diverse as carrying nutrients across the plasma membrane, receiving chemical signals …