Advances and prospects in tumor infiltrating lymphocyte therapy

X Qiu, S Li, T Fan, Y Zhang, B Wang, B Zhang… - Discover Oncology, 2024 - Springer
Tumor-infiltrating lymphocyte (TIL) therapy in adoptive T-cell therapy (ACT) has already
caused durable regression in a variety of cancer types due to T-cell persistence, clinical …

[HTML][HTML] Depletion of high-content CD14+ cells from apheresis products is critical for successful transduction and expansion of CAR T cells during large-scale cGMP …

X Wang, O Borquez-Ojeda, J Stefanski, F Du… - … Therapy Methods & …, 2021 - cell.com
With the US Food and Drug Administration (FDA) approval of four CD19-and one BCMA-
targeted chimeric antigen receptor (CAR) therapy for B cell malignancies, CAR T cell …

Reverse-engineering the FLT3-PI3K/AKT axis to enhance TILs function and improve prognosis in ovarian and cervical cancers

F Hao, Z Yan, L Shen, W Hui, Q Ling, Y Xiaoyu… - Journal of Ovarian …, 2025 - Springer
Background Ovarian cancers (OC) and cervical cancers (CC) have poor survival rates.
Tumor-infiltrating lymphocytes (TILs) play a pivotal role in prognosis, but shared immune …

The signature genes of cuproptosis associates with tumor immune microenvironment and predicts prognosis in kidney renal clear cell carcinoma

S Liu, S Lv, X Li, W Lu, S Chen - Frontiers in Oncology, 2024 - pmc.ncbi.nlm.nih.gov
Background Cuproptosis is a new form of cell death, which has great potential to be
developed in tumors treatment. Our study aimed to explore the predictive value of …

Tumor infiltrating lymphocyte therapy for renal cell carcinoma: methods for ex vivo expansion and T-cell memory induction

MW Braun - 2021 - search.proquest.com
Tumor infiltrating lymphocyte (TIL) therapy is a personalized treatment for locally advanced
or metastatic cancer. TIL therapy requires the surgical excision of a portion of the malignant …